A rare cause of posterior reversible encephalopathy syndrome: Acute lymphoblastic leukemia

Key Clinical Message The presentation of posterior reversible encephalopathy syndrome (PRES) as the initial presenting sign of acute lymphoblastic leukemia is unusual, as PRES is more often a complication of therapy. This case highlights the importance of maintaining a broad differential diagnosis f...

Full description

Bibliographic Details
Main Authors: Jessica Hayes, Anne Byrd Mahoney, Claci Ayers, Asha Sarma, Kevin C. Ess, Tracy E. Hunley, Christine Moore Smith
Format: Article
Language:English
Published: Wiley 2023-11-01
Series:Clinical Case Reports
Subjects:
Online Access:https://doi.org/10.1002/ccr3.8238
_version_ 1797449721328959488
author Jessica Hayes
Anne Byrd Mahoney
Claci Ayers
Asha Sarma
Kevin C. Ess
Tracy E. Hunley
Christine Moore Smith
author_facet Jessica Hayes
Anne Byrd Mahoney
Claci Ayers
Asha Sarma
Kevin C. Ess
Tracy E. Hunley
Christine Moore Smith
author_sort Jessica Hayes
collection DOAJ
description Key Clinical Message The presentation of posterior reversible encephalopathy syndrome (PRES) as the initial presenting sign of acute lymphoblastic leukemia is unusual, as PRES is more often a complication of therapy. This case highlights the importance of maintaining a broad differential diagnosis for pediatric hypertension and its complications. Abstract A 6‐year‐old male presented with a seizure‐like episode. Evaluation revealed hypertension and brain imaging showed findings consistent with posterior reversible encephalopathy syndrome. Complete blood count showed lymphoblasts, and the cause of his hypertension was determined to be renal infiltration of leukemia cells due to B‐cell acute lymphoblastic leukemia.
first_indexed 2024-03-09T14:30:08Z
format Article
id doaj.art-cd4d81930a42484f8a731cd764eeabbd
institution Directory Open Access Journal
issn 2050-0904
language English
last_indexed 2024-03-09T14:30:08Z
publishDate 2023-11-01
publisher Wiley
record_format Article
series Clinical Case Reports
spelling doaj.art-cd4d81930a42484f8a731cd764eeabbd2023-11-28T04:14:45ZengWileyClinical Case Reports2050-09042023-11-011111n/an/a10.1002/ccr3.8238A rare cause of posterior reversible encephalopathy syndrome: Acute lymphoblastic leukemiaJessica Hayes0Anne Byrd Mahoney1Claci Ayers2Asha Sarma3Kevin C. Ess4Tracy E. Hunley5Christine Moore Smith6Department of Pediatrics, Vanderbilt University Medical Center Monroe Carell Jr. Children's Hospital Nashville Tennessee USADepartment of Pediatrics, Vanderbilt University Medical Center Monroe Carell Jr. Children's Hospital Nashville Tennessee USADepartment of Pediatrics, Vanderbilt University Medical Center Monroe Carell Jr. Children's Hospital Nashville Tennessee USADepartment of Radiology Vanderbilt University Medical Center Nashville Tennessee USADepartment of Pediatrics, Vanderbilt University Medical Center Monroe Carell Jr. Children's Hospital Nashville Tennessee USADepartment of Pediatrics, Vanderbilt University Medical Center Monroe Carell Jr. Children's Hospital Nashville Tennessee USADepartment of Pediatrics, Vanderbilt University Medical Center Monroe Carell Jr. Children's Hospital Nashville Tennessee USAKey Clinical Message The presentation of posterior reversible encephalopathy syndrome (PRES) as the initial presenting sign of acute lymphoblastic leukemia is unusual, as PRES is more often a complication of therapy. This case highlights the importance of maintaining a broad differential diagnosis for pediatric hypertension and its complications. Abstract A 6‐year‐old male presented with a seizure‐like episode. Evaluation revealed hypertension and brain imaging showed findings consistent with posterior reversible encephalopathy syndrome. Complete blood count showed lymphoblasts, and the cause of his hypertension was determined to be renal infiltration of leukemia cells due to B‐cell acute lymphoblastic leukemia.https://doi.org/10.1002/ccr3.8238ALLemergency medicinenephrologyoncologypediatric hypertensionpediatrics and adolescent medicine
spellingShingle Jessica Hayes
Anne Byrd Mahoney
Claci Ayers
Asha Sarma
Kevin C. Ess
Tracy E. Hunley
Christine Moore Smith
A rare cause of posterior reversible encephalopathy syndrome: Acute lymphoblastic leukemia
Clinical Case Reports
ALL
emergency medicine
nephrology
oncology
pediatric hypertension
pediatrics and adolescent medicine
title A rare cause of posterior reversible encephalopathy syndrome: Acute lymphoblastic leukemia
title_full A rare cause of posterior reversible encephalopathy syndrome: Acute lymphoblastic leukemia
title_fullStr A rare cause of posterior reversible encephalopathy syndrome: Acute lymphoblastic leukemia
title_full_unstemmed A rare cause of posterior reversible encephalopathy syndrome: Acute lymphoblastic leukemia
title_short A rare cause of posterior reversible encephalopathy syndrome: Acute lymphoblastic leukemia
title_sort rare cause of posterior reversible encephalopathy syndrome acute lymphoblastic leukemia
topic ALL
emergency medicine
nephrology
oncology
pediatric hypertension
pediatrics and adolescent medicine
url https://doi.org/10.1002/ccr3.8238
work_keys_str_mv AT jessicahayes ararecauseofposteriorreversibleencephalopathysyndromeacutelymphoblasticleukemia
AT annebyrdmahoney ararecauseofposteriorreversibleencephalopathysyndromeacutelymphoblasticleukemia
AT claciayers ararecauseofposteriorreversibleencephalopathysyndromeacutelymphoblasticleukemia
AT ashasarma ararecauseofposteriorreversibleencephalopathysyndromeacutelymphoblasticleukemia
AT kevincess ararecauseofposteriorreversibleencephalopathysyndromeacutelymphoblasticleukemia
AT tracyehunley ararecauseofposteriorreversibleencephalopathysyndromeacutelymphoblasticleukemia
AT christinemooresmith ararecauseofposteriorreversibleencephalopathysyndromeacutelymphoblasticleukemia
AT jessicahayes rarecauseofposteriorreversibleencephalopathysyndromeacutelymphoblasticleukemia
AT annebyrdmahoney rarecauseofposteriorreversibleencephalopathysyndromeacutelymphoblasticleukemia
AT claciayers rarecauseofposteriorreversibleencephalopathysyndromeacutelymphoblasticleukemia
AT ashasarma rarecauseofposteriorreversibleencephalopathysyndromeacutelymphoblasticleukemia
AT kevincess rarecauseofposteriorreversibleencephalopathysyndromeacutelymphoblasticleukemia
AT tracyehunley rarecauseofposteriorreversibleencephalopathysyndromeacutelymphoblasticleukemia
AT christinemooresmith rarecauseofposteriorreversibleencephalopathysyndromeacutelymphoblasticleukemia