New Cytotoxic and Antibacterial Compounds Isolated from the Sea Hare, Aplysia kurodai
Abstract: The extract of the sea hare, Aplysia kurodai, showed cytotoxicity against HeLa cells and antibacterial activity against Staphylococcus aureus. Bioassay-guided purification afforded four active compounds, which were identified to be laurinterol, laurinterol acetate, debromolaurinterol, and...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2005-04-01
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| Series: | Marine Drugs |
| Subjects: | |
| Online Access: | http://www.mdpi.com/1660-3397/3/2/22/ |
| _version_ | 1798042147593650176 |
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| author | Tomihisa Ohta Yuko Yamashita Sachiko Tsukamoto |
| author_facet | Tomihisa Ohta Yuko Yamashita Sachiko Tsukamoto |
| author_sort | Tomihisa Ohta |
| collection | DOAJ |
| description | Abstract: The extract of the sea hare, Aplysia kurodai, showed cytotoxicity against HeLa cells and antibacterial activity against Staphylococcus aureus. Bioassay-guided purification afforded four active compounds, which were identified to be laurinterol, laurinterol acetate, debromolaurinterol, and debromolaurinterol acetate by spectroscopic analysis. Although the acetates were derived from laurinterol and debromolaurinterol before, this is the first isolation of the acetates from natural sources. |
| first_indexed | 2024-04-11T22:31:27Z |
| format | Article |
| id | doaj.art-cd4d837a0dbb41c3a10f8f0f366ded95 |
| institution | Directory Open Access Journal |
| issn | 1660-3397 |
| language | English |
| last_indexed | 2024-04-11T22:31:27Z |
| publishDate | 2005-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Marine Drugs |
| spelling | doaj.art-cd4d837a0dbb41c3a10f8f0f366ded952022-12-22T03:59:24ZengMDPI AGMarine Drugs1660-33972005-04-0132222810.3390/md302022New Cytotoxic and Antibacterial Compounds Isolated from the Sea Hare, Aplysia kurodaiTomihisa OhtaYuko YamashitaSachiko TsukamotoAbstract: The extract of the sea hare, Aplysia kurodai, showed cytotoxicity against HeLa cells and antibacterial activity against Staphylococcus aureus. Bioassay-guided purification afforded four active compounds, which were identified to be laurinterol, laurinterol acetate, debromolaurinterol, and debromolaurinterol acetate by spectroscopic analysis. Although the acetates were derived from laurinterol and debromolaurinterol before, this is the first isolation of the acetates from natural sources.http://www.mdpi.com/1660-3397/3/2/22/cytotoxicityantibacterial activitylaurinterol acetatedebromolaurinterol acetatesea hareAplysia kurodai |
| spellingShingle | Tomihisa Ohta Yuko Yamashita Sachiko Tsukamoto New Cytotoxic and Antibacterial Compounds Isolated from the Sea Hare, Aplysia kurodai Marine Drugs cytotoxicity antibacterial activity laurinterol acetate debromolaurinterol acetate sea hare Aplysia kurodai |
| title | New Cytotoxic and Antibacterial Compounds Isolated from the Sea Hare, Aplysia kurodai |
| title_full | New Cytotoxic and Antibacterial Compounds Isolated from the Sea Hare, Aplysia kurodai |
| title_fullStr | New Cytotoxic and Antibacterial Compounds Isolated from the Sea Hare, Aplysia kurodai |
| title_full_unstemmed | New Cytotoxic and Antibacterial Compounds Isolated from the Sea Hare, Aplysia kurodai |
| title_short | New Cytotoxic and Antibacterial Compounds Isolated from the Sea Hare, Aplysia kurodai |
| title_sort | new cytotoxic and antibacterial compounds isolated from the sea hare aplysia kurodai |
| topic | cytotoxicity antibacterial activity laurinterol acetate debromolaurinterol acetate sea hare Aplysia kurodai |
| url | http://www.mdpi.com/1660-3397/3/2/22/ |
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