Estrogen receptor signaling regulates the expression of the breast tumor kinase in breast cancer cells

Estrogen receptor signaling regulates the expression of the breast tumor kinase in breast cancer cells

Abstract Background BRK is, a non-receptor tyrosine kinase, overexpressed in approximately 85% of human invasive ductal breast tumors. It is not clear whether BRK expression correlates with breast cancer subtypes, or the expression has prognostic or diagnostic significance. Herein, we investigated t...

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Bibliographic Details
Main Authors: Sayem Miah, Edward Bagu, Raghuveera Goel, Yetunde Ogunbolude, Chenlu Dai, Alison Ward, Frederick S. Vizeacoumar, Gerald Davies, Franco J. Vizeacoumar, Deborah Anderson, Kiven Erique Lukong
Format: Article
Language:English
Published: BMC 2019-01-01
Series:BMC Cancer
Subjects:
BRK
Tamoxifen
Estrogen receptor
Breast cancer
Tyrosine kinase
Online Access:http://link.springer.com/article/10.1186/s12885-018-5186-8

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