Oximetry at admission as a predictor of tomographic and functional impairment after 3–6 months in hospitalized patients with COVID-19
Objective To investigate characteristics that may be associated with radiologic and functional findings following discharge in patients with severe coronavirus disease 2019 (COVID-19). Methods This single-center, prospective, observational cohort study comprised patients aged >18 years who were h...
| Main Authors: | , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2023-06-01
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| Series: | Journal of International Medical Research |
| Online Access: | https://doi.org/10.1177/03000605231177187 |
| _version_ | 1797807270689505280 |
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| author | Pedro Maximink Esteves Villar Paulo Roberto Araújo Mendes Tatiana Alves Kiyota Henrique Alcântara Engleitner Carolina Salem Tamesawa Mayara Magalhães Morello Nayara Nobre Basso Lucas Fileti Arruda Bruna Scharlack Vian Lígia dos Santos Roceto Ratti Laís Bacchin de Oliveira Ana Lucia Cavallaro Baraúna Lima Hugo Dugolin Ceccato Julian Furtado Silva Wander de Oliveira Villalba Lucieni de Oliveira Conterno Mariângela Ribeiro Resende Mônica Corso Pereira |
| author_facet | Pedro Maximink Esteves Villar Paulo Roberto Araújo Mendes Tatiana Alves Kiyota Henrique Alcântara Engleitner Carolina Salem Tamesawa Mayara Magalhães Morello Nayara Nobre Basso Lucas Fileti Arruda Bruna Scharlack Vian Lígia dos Santos Roceto Ratti Laís Bacchin de Oliveira Ana Lucia Cavallaro Baraúna Lima Hugo Dugolin Ceccato Julian Furtado Silva Wander de Oliveira Villalba Lucieni de Oliveira Conterno Mariângela Ribeiro Resende Mônica Corso Pereira |
| author_sort | Pedro Maximink Esteves Villar |
| collection | DOAJ |
| description | Objective To investigate characteristics that may be associated with radiologic and functional findings following discharge in patients with severe coronavirus disease 2019 (COVID-19). Methods This single-center, prospective, observational cohort study comprised patients aged >18 years who were hospitalized with COVID-19 pneumonia, between May and October 2020. After 3 to 6 months of discharge, patients were clinically evaluated and underwent spirometry, a 6-minute walk test (6MWT), and chest computed tomography (CT). Statistical analysis was performed using association and correlation tests. Results A total of 134 patients were included (25/114 [22%] were admitted with severe hypoxemia). On the follow-up chest CT, 29/92 (32%) had no abnormalities, regardless of the severity of the initial involvement, and the mean 6MWT distance was 447 m. Patients with desaturation on admission had an increased risk of remaining CT abnormalities: patients with SpO 2 between 88 and 92% had a 4.0-fold risk, and those with SpO 2 < 88% had a 6.2-fold risk. The group with SpO 2 < 88% also walked shorter distances than patients with SpO 2 between 88 and 92%. Conclusion Initial hypoxemia was found to be a good predictor of persistent radiological abnormalities in follow-up and was associated with low performance in 6MWT. |
| first_indexed | 2024-03-13T06:21:04Z |
| format | Article |
| id | doaj.art-cd5238fcd28d44fa971c1b4e8af36e7b |
| institution | Directory Open Access Journal |
| issn | 1473-2300 |
| language | English |
| last_indexed | 2024-03-13T06:21:04Z |
| publishDate | 2023-06-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Journal of International Medical Research |
| spelling | doaj.art-cd5238fcd28d44fa971c1b4e8af36e7b2023-06-09T20:33:22ZengSAGE PublishingJournal of International Medical Research1473-23002023-06-015110.1177/03000605231177187Oximetry at admission as a predictor of tomographic and functional impairment after 3–6 months in hospitalized patients with COVID-19Pedro Maximink Esteves VillarPaulo Roberto Araújo MendesTatiana Alves KiyotaHenrique Alcântara EngleitnerCarolina Salem TamesawaMayara Magalhães MorelloNayara Nobre BassoLucas Fileti ArrudaBruna Scharlack VianLígia dos Santos Roceto RattiLaís Bacchin de OliveiraAna Lucia Cavallaro Baraúna LimaHugo Dugolin CeccatoJulian Furtado SilvaWander de Oliveira VillalbaLucieni de Oliveira ConternoMariângela Ribeiro ResendeMônica Corso PereiraObjective To investigate characteristics that may be associated with radiologic and functional findings following discharge in patients with severe coronavirus disease 2019 (COVID-19). Methods This single-center, prospective, observational cohort study comprised patients aged >18 years who were hospitalized with COVID-19 pneumonia, between May and October 2020. After 3 to 6 months of discharge, patients were clinically evaluated and underwent spirometry, a 6-minute walk test (6MWT), and chest computed tomography (CT). Statistical analysis was performed using association and correlation tests. Results A total of 134 patients were included (25/114 [22%] were admitted with severe hypoxemia). On the follow-up chest CT, 29/92 (32%) had no abnormalities, regardless of the severity of the initial involvement, and the mean 6MWT distance was 447 m. Patients with desaturation on admission had an increased risk of remaining CT abnormalities: patients with SpO 2 between 88 and 92% had a 4.0-fold risk, and those with SpO 2 < 88% had a 6.2-fold risk. The group with SpO 2 < 88% also walked shorter distances than patients with SpO 2 between 88 and 92%. Conclusion Initial hypoxemia was found to be a good predictor of persistent radiological abnormalities in follow-up and was associated with low performance in 6MWT.https://doi.org/10.1177/03000605231177187 |
| spellingShingle | Pedro Maximink Esteves Villar Paulo Roberto Araújo Mendes Tatiana Alves Kiyota Henrique Alcântara Engleitner Carolina Salem Tamesawa Mayara Magalhães Morello Nayara Nobre Basso Lucas Fileti Arruda Bruna Scharlack Vian Lígia dos Santos Roceto Ratti Laís Bacchin de Oliveira Ana Lucia Cavallaro Baraúna Lima Hugo Dugolin Ceccato Julian Furtado Silva Wander de Oliveira Villalba Lucieni de Oliveira Conterno Mariângela Ribeiro Resende Mônica Corso Pereira Oximetry at admission as a predictor of tomographic and functional impairment after 3–6 months in hospitalized patients with COVID-19 Journal of International Medical Research |
| title | Oximetry at admission as a predictor of tomographic and functional impairment after 3–6 months in hospitalized patients with COVID-19 |
| title_full | Oximetry at admission as a predictor of tomographic and functional impairment after 3–6 months in hospitalized patients with COVID-19 |
| title_fullStr | Oximetry at admission as a predictor of tomographic and functional impairment after 3–6 months in hospitalized patients with COVID-19 |
| title_full_unstemmed | Oximetry at admission as a predictor of tomographic and functional impairment after 3–6 months in hospitalized patients with COVID-19 |
| title_short | Oximetry at admission as a predictor of tomographic and functional impairment after 3–6 months in hospitalized patients with COVID-19 |
| title_sort | oximetry at admission as a predictor of tomographic and functional impairment after 3 6 months in hospitalized patients with covid 19 |
| url | https://doi.org/10.1177/03000605231177187 |
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