Global methylation status of sperm DNA in carriers of chromosome structural aberrations

Global methylation status of sperm DNA in carriers of chromosome structural aberrations

Male infertility might be clearly associated with aberrant DNA methylation patterns in human spermatozoa. An association between oxidative stress and the global methylation status of the sperm genome has also been suggested. The aim of the present study was to determine whether the global sperm DNA...

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Bibliographic Details
Main Authors: Marta Olszewska, Miroslawa Z Barciszewska, Monika Fraczek, Nataliya Huleyuk, Vyacheslav B Chernykh, Danuta Zastavna, Jan Barciszewski, Maciej Kurpisz
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:Asian Journal of Andrology
Subjects:
5-methylcytosine; chromatin integrity; chromosomal rearrangement; chromosome translocation; global DNA methylation; male infertility
Online Access:http://www.ajandrology.com/article.asp?issn=1008-682X;year=2017;volume=19;issue=1;spage=117;epage=124;aulast=Olszewska

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