Bakteri dalam Plak Gigi dan Saliva Penderita Diabetes Tipe 2, dan Hubungannya dengan Status Agregasi Trombosit
The occurrence of coronary atherosclerosis and acute myocardianl ischemia due to the hyperaggregation of platelets, caused the death of 75-80% of type 2 diabetics. In an invitro study, the aggregation of platelets was influenced by the "Platelet Aggregation Associated Protein" on the surfa...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Faculty of Dentistry, Universitas Indonesia
2015-09-01
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| Series: | Journal of Dentistry Indonesia |
| Online Access: | http://jdentistry.ui.ac.id/index.php/JDI/article/view/727 |
| Summary: | The occurrence of coronary atherosclerosis and acute myocardianl ischemia due to the hyperaggregation of platelets, caused the death of 75-80% of type 2 diabetics. In an invitro study, the aggregation of platelets was influenced by the "Platelet Aggregation Associated Protein" on the surface of dental plaque bacteria, <em>S. sanguis. </em>The aim of the study was to identify bacteria in the supragingival plaque and saliva of type 2 diabetics, and their relationship to the aggregation of platelets. Dental plaque and salivary gland samples from 5 type 2 diabetics were diluted serially, and inoculated in Mitis Salivarius medium. The morphologie of the Colony Forming Units (CFU) Growth were analysed, identified physiologically and biochemically with Api 20 Strep subtrates. Aggregation of platelets of the blood were analysed with Adenosin Di Phosphate. The result of the study showed 22 colonies (CFU), in 6 morphology types. Three morphologytypes were identified as <em>A viridans</em>, the other 3 as <em>Str. acidominus, Lc. lactis lactis,</em> and <em>E. avium.</em> One morphology type of <em>A. viridans, Str .acidominus, Lc. lactis lactis</em> and <em>E. avium</em> were found in subjects with hypoaggregation; 2 morphology types <em>of A. viridans</em> were found in subjects with normal aggregation. It is presumed that type 2 diabetics with <em>Str. acidominus, Lc. lactis actis, E. avium, </em>and certain morphology type o<em>f A. viridans</em> in their dental plaque and saliva, hve hyperaggregation of platelet diabetics with two morphology types of <em>A. viridans</em> have normal aggregation of platelets. |
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| ISSN: | 1693-9697 2355-4800 |