Anti-hyperlipidemic effect of Hridayarnava Rasa - A randomized double blind clinical study

Background: Hyperlipidemia is modifiable risk factor for cardiovascular diseases, and its prevalence is alarmingly increasing in India. Though different treatment modalities are effectively used in the conventional system, they have certain limitations including certain adverse effects. Ayurvedic me...

Full description

Bibliographic Details
Main Authors: Chaudhari Swapnil, R Galib, B J Patgiri, P K Prajapati
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Indian Journal of Ayurveda and Integrative Medicine KLEU
Subjects:
Online Access:http://www.ijaim.in/article.asp?issn=2772-6010;year=2019;volume=1;issue=1;spage=4;epage=10;aulast=Swapnil
_version_ 1797866665291022336
author Chaudhari Swapnil
R Galib
B J Patgiri
P K Prajapati
author_facet Chaudhari Swapnil
R Galib
B J Patgiri
P K Prajapati
author_sort Chaudhari Swapnil
collection DOAJ
description Background: Hyperlipidemia is modifiable risk factor for cardiovascular diseases, and its prevalence is alarmingly increasing in India. Though different treatment modalities are effectively used in the conventional system, they have certain limitations including certain adverse effects. Ayurvedic metallic and herbo-mineral formulations are safely practiced in Indian subcontinent without any evident side effects. Hridayarnava Rasa is one such Ayurvedic herbo-metalo-mineral formulation containing Tamra Bhasma (incinerated copper) that is being successfully prescribed in the management of lipid disorders. Aims and Objectives: To evaluate antihyperlipidemic effect of two samples of Hridayarnava Rasa prepared by using Tamra Bhasma processed in Surana Kanda (HRTBS) and Panchamrita during Amritikarana (HRTBP). Materials and methods: Total 126 patients of hyperlipidemia fulfilling inclusion criteria were randomly grouped into two. Patients registered in one group (n = 62) were administered with 125 mg of HRTBP (Hridayarnava Rasa prepared by using Tamra Bhasma processed in Panchamrita for Amritikarana) and another Group (n =64) with HRTBS (Hridayarnava Rasa prepared by using Tamra Bhasma processed in Suranakanda for Amritikarana) twice daily for 8 weeks along with honey as an adjuvant in both groups. Results and Conclusion: Both the drugs have shown significant effect in reducing lipid parameters but the difference in between the groups is statistically insignificant. On comparison, HRTBP showed better results than HRTBS.
first_indexed 2024-04-09T23:28:58Z
format Article
id doaj.art-cd57e7b3b7b34856aa34bdb9d708e5d9
institution Directory Open Access Journal
issn 2772-6010
2772-6029
language English
last_indexed 2024-04-09T23:28:58Z
publishDate 2019-01-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Indian Journal of Ayurveda and Integrative Medicine KLEU
spelling doaj.art-cd57e7b3b7b34856aa34bdb9d708e5d92023-03-21T07:35:06ZengWolters Kluwer Medknow PublicationsIndian Journal of Ayurveda and Integrative Medicine KLEU2772-60102772-60292019-01-0111410Anti-hyperlipidemic effect of Hridayarnava Rasa - A randomized double blind clinical studyChaudhari SwapnilR GalibB J PatgiriP K PrajapatiBackground: Hyperlipidemia is modifiable risk factor for cardiovascular diseases, and its prevalence is alarmingly increasing in India. Though different treatment modalities are effectively used in the conventional system, they have certain limitations including certain adverse effects. Ayurvedic metallic and herbo-mineral formulations are safely practiced in Indian subcontinent without any evident side effects. Hridayarnava Rasa is one such Ayurvedic herbo-metalo-mineral formulation containing Tamra Bhasma (incinerated copper) that is being successfully prescribed in the management of lipid disorders. Aims and Objectives: To evaluate antihyperlipidemic effect of two samples of Hridayarnava Rasa prepared by using Tamra Bhasma processed in Surana Kanda (HRTBS) and Panchamrita during Amritikarana (HRTBP). Materials and methods: Total 126 patients of hyperlipidemia fulfilling inclusion criteria were randomly grouped into two. Patients registered in one group (n = 62) were administered with 125 mg of HRTBP (Hridayarnava Rasa prepared by using Tamra Bhasma processed in Panchamrita for Amritikarana) and another Group (n =64) with HRTBS (Hridayarnava Rasa prepared by using Tamra Bhasma processed in Suranakanda for Amritikarana) twice daily for 8 weeks along with honey as an adjuvant in both groups. Results and Conclusion: Both the drugs have shown significant effect in reducing lipid parameters but the difference in between the groups is statistically insignificant. On comparison, HRTBP showed better results than HRTBS.http://www.ijaim.in/article.asp?issn=2772-6010;year=2019;volume=1;issue=1;spage=4;epage=10;aulast=Swapnilcopperhridayarnava rasahyperlipidemiatamra
spellingShingle Chaudhari Swapnil
R Galib
B J Patgiri
P K Prajapati
Anti-hyperlipidemic effect of Hridayarnava Rasa - A randomized double blind clinical study
Indian Journal of Ayurveda and Integrative Medicine KLEU
copper
hridayarnava rasa
hyperlipidemia
tamra
title Anti-hyperlipidemic effect of Hridayarnava Rasa - A randomized double blind clinical study
title_full Anti-hyperlipidemic effect of Hridayarnava Rasa - A randomized double blind clinical study
title_fullStr Anti-hyperlipidemic effect of Hridayarnava Rasa - A randomized double blind clinical study
title_full_unstemmed Anti-hyperlipidemic effect of Hridayarnava Rasa - A randomized double blind clinical study
title_short Anti-hyperlipidemic effect of Hridayarnava Rasa - A randomized double blind clinical study
title_sort anti hyperlipidemic effect of hridayarnava rasa a randomized double blind clinical study
topic copper
hridayarnava rasa
hyperlipidemia
tamra
url http://www.ijaim.in/article.asp?issn=2772-6010;year=2019;volume=1;issue=1;spage=4;epage=10;aulast=Swapnil
work_keys_str_mv AT chaudhariswapnil antihyperlipidemiceffectofhridayarnavarasaarandomizeddoubleblindclinicalstudy
AT rgalib antihyperlipidemiceffectofhridayarnavarasaarandomizeddoubleblindclinicalstudy
AT bjpatgiri antihyperlipidemiceffectofhridayarnavarasaarandomizeddoubleblindclinicalstudy
AT pkprajapati antihyperlipidemiceffectofhridayarnavarasaarandomizeddoubleblindclinicalstudy