Ribosomopathies: Mechanisms of Disease
Ribosomopathies are diseases caused by alterations in the structure or function of ribosomal components. Progress in our understanding of the role of the ribosome in translational and transcriptional regulation has clarified the mechanisms of the ribosomopathies and the relationship between ribosoma...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2014-01-01
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| Series: | Clinical Medicine Insights: Blood Disorders |
| Online Access: | https://doi.org/10.4137/CMBD.S16952 |
| _version_ | 1819008780811108352 |
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| author | Hani Nakhoul Jiangwei Ke Xiang Zhou Wenjuan Liao Shelya X. Zeng Hua Lu |
| author_facet | Hani Nakhoul Jiangwei Ke Xiang Zhou Wenjuan Liao Shelya X. Zeng Hua Lu |
| author_sort | Hani Nakhoul |
| collection | DOAJ |
| description | Ribosomopathies are diseases caused by alterations in the structure or function of ribosomal components. Progress in our understanding of the role of the ribosome in translational and transcriptional regulation has clarified the mechanisms of the ribosomopathies and the relationship between ribosomal dysfunction and other diseases, especially cancer. This review aims to discuss these topics with updated information. |
| first_indexed | 2024-12-21T00:45:55Z |
| format | Article |
| id | doaj.art-cd57ede907f44548b6f58aac3e5ab81e |
| institution | Directory Open Access Journal |
| issn | 1179-545X |
| language | English |
| last_indexed | 2024-12-21T00:45:55Z |
| publishDate | 2014-01-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Clinical Medicine Insights: Blood Disorders |
| spelling | doaj.art-cd57ede907f44548b6f58aac3e5ab81e2022-12-21T19:21:31ZengSAGE PublishingClinical Medicine Insights: Blood Disorders1179-545X2014-01-01710.4137/CMBD.S16952Ribosomopathies: Mechanisms of DiseaseHani Nakhoul0Jiangwei Ke1Xiang Zhou2Wenjuan Liao3Shelya X. Zeng4Hua Lu5Department of Biochemistry and Molecular Biology and Cancer Center, Tulane University, School of Medicine, New Orleans, Louisiana, LA, USA.Department of Laboratory Medicine, Jiangxi Children's Hospital, Nanchang, Jiangxi, China.Department of Biochemistry and Molecular Biology and Cancer Center, Tulane University, School of Medicine, New Orleans, Louisiana, LA, USA.Department of Biochemistry and Molecular Biology and Cancer Center, Tulane University, School of Medicine, New Orleans, Louisiana, LA, USA.Department of Biochemistry and Molecular Biology and Cancer Center, Tulane University, School of Medicine, New Orleans, Louisiana, LA, USA.Department of Biochemistry and Molecular Biology and Cancer Center, Tulane University, School of Medicine, New Orleans, Louisiana, LA, USA.Ribosomopathies are diseases caused by alterations in the structure or function of ribosomal components. Progress in our understanding of the role of the ribosome in translational and transcriptional regulation has clarified the mechanisms of the ribosomopathies and the relationship between ribosomal dysfunction and other diseases, especially cancer. This review aims to discuss these topics with updated information.https://doi.org/10.4137/CMBD.S16952 |
| spellingShingle | Hani Nakhoul Jiangwei Ke Xiang Zhou Wenjuan Liao Shelya X. Zeng Hua Lu Ribosomopathies: Mechanisms of Disease Clinical Medicine Insights: Blood Disorders |
| title | Ribosomopathies: Mechanisms of Disease |
| title_full | Ribosomopathies: Mechanisms of Disease |
| title_fullStr | Ribosomopathies: Mechanisms of Disease |
| title_full_unstemmed | Ribosomopathies: Mechanisms of Disease |
| title_short | Ribosomopathies: Mechanisms of Disease |
| title_sort | ribosomopathies mechanisms of disease |
| url | https://doi.org/10.4137/CMBD.S16952 |
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