Point-of-Care Echocardiographic Characteristics of COVID-19 Patients with Pulmonary Embolism
Introduction: Thrombotic complications, such as pulmonary embolism, are common in COVID-19 patients. Point-of-care ultrasound is a highly recommended tool for orientation in critically ill patients with suspected or confirmed complications. Methods: An observational study was conducted on 32 consecu...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-09-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/12/10/2380 |
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| author | Slobodan Klasnja Andrea Manojlovic Viseslav Popadic Tatjana Ivankovic Nebojsa Ninkovic Nina Rajovic Maja Popovic Novica Nikolic Milica Brajkovic Aleksandra Radojevic Ratko Lasica Sasa Rajsic Zoran Todorovic Marija Brankovic Tijana Radonjic Lidija Memon Davor Mrda Natasa Milic Marija Zdravkovic |
| author_facet | Slobodan Klasnja Andrea Manojlovic Viseslav Popadic Tatjana Ivankovic Nebojsa Ninkovic Nina Rajovic Maja Popovic Novica Nikolic Milica Brajkovic Aleksandra Radojevic Ratko Lasica Sasa Rajsic Zoran Todorovic Marija Brankovic Tijana Radonjic Lidija Memon Davor Mrda Natasa Milic Marija Zdravkovic |
| author_sort | Slobodan Klasnja |
| collection | DOAJ |
| description | Introduction: Thrombotic complications, such as pulmonary embolism, are common in COVID-19 patients. Point-of-care ultrasound is a highly recommended tool for orientation in critically ill patients with suspected or confirmed complications. Methods: An observational study was conducted on 32 consecutive patients with confirmed pulmonary embolism and COVID-19 infection treated in the Intensive Care Unit of the University Hospital Medical Center “Bežanijska kosa”, Belgrade, Serbia, between April 2021 and March 2022. Predictors of the need for oxygen support were determined, while point-of-care echocardiographic parameters and various anamnestic, laboratory, and clinically significant parameters were correlated with the Pulmonary Embolism Severity Index (PESI) score. Results: More than two-thirds of patients in our study had PE symptoms present at hospital admission (68.8%). The majority of patients had segmental pulmonary embolism (48.4%), with high to very high PESI score values in 31.3% of patients. Pneumonia was present in 68.8% of the study population. The PESI score was negatively correlated with diastolic blood pressure and SaO2 at the time of PE diagnosis, LV ejection fraction, and PVAT. A positive correlation was found between the PESI score, maximum CRP, and D-dimer at the time of PTE diagnosis. A larger right ventricular diameter was associated with a greater need for oxygen support. Conclusion: Point-of-care echocardiography is a valuable tool for the risk assessment of COVID-19 patients with pulmonary embolism. Right ventricular size stood out as a significant marker of disease severity. |
| first_indexed | 2024-03-09T20:22:41Z |
| format | Article |
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| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-09T20:22:41Z |
| publishDate | 2022-09-01 |
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| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-cd58fc1cfb294e958cbda65275f738a02023-11-23T23:44:14ZengMDPI AGDiagnostics2075-44182022-09-011210238010.3390/diagnostics12102380Point-of-Care Echocardiographic Characteristics of COVID-19 Patients with Pulmonary EmbolismSlobodan Klasnja0Andrea Manojlovic1Viseslav Popadic2Tatjana Ivankovic3Nebojsa Ninkovic4Nina Rajovic5Maja Popovic6Novica Nikolic7Milica Brajkovic8Aleksandra Radojevic9Ratko Lasica10Sasa Rajsic11Zoran Todorovic12Marija Brankovic13Tijana Radonjic14Lidija Memon15Davor Mrda16Natasa Milic17Marija Zdravkovic18University Hospital Medical Center Bežanijska kosa, 11000 Belgrade, SerbiaUniversity Hospital Medical Center Bežanijska kosa, 11000 Belgrade, SerbiaUniversity Hospital Medical Center Bežanijska kosa, 11000 Belgrade, SerbiaUniversity Hospital Medical Center Bežanijska kosa, 11000 Belgrade, SerbiaUniversity Hospital Medical Center Bežanijska kosa, 11000 Belgrade, SerbiaInstitute for Medical Statistics and Informatics, Faculty of Medicine, University of Belgrade, 11000 Belgrade, SerbiaUniversity Hospital Medical Center Bežanijska kosa, 11000 Belgrade, SerbiaUniversity Hospital Medical Center Bežanijska kosa, 11000 Belgrade, SerbiaUniversity Hospital Medical Center Bežanijska kosa, 11000 Belgrade, SerbiaUniversity Hospital Medical Center Bežanijska kosa, 11000 Belgrade, SerbiaUniversity Clinical Center of Serbia, 11000 Belgrade, SerbiaDepartment of Anaesthesiology and Intensive Care Medicine, Medical University Innsbruck, 6020 Innsbruck, AustriaUniversity Hospital Medical Center Bežanijska kosa, 11000 Belgrade, SerbiaUniversity Hospital Medical Center Bežanijska kosa, 11000 Belgrade, SerbiaUniversity Hospital Medical Center Bežanijska kosa, 11000 Belgrade, SerbiaUniversity Hospital Medical Center Bežanijska kosa, 11000 Belgrade, SerbiaUniversity Hospital Medical Center Bežanijska kosa, 11000 Belgrade, SerbiaInstitute for Medical Statistics and Informatics, Faculty of Medicine, University of Belgrade, 11000 Belgrade, SerbiaUniversity Hospital Medical Center Bežanijska kosa, 11000 Belgrade, SerbiaIntroduction: Thrombotic complications, such as pulmonary embolism, are common in COVID-19 patients. Point-of-care ultrasound is a highly recommended tool for orientation in critically ill patients with suspected or confirmed complications. Methods: An observational study was conducted on 32 consecutive patients with confirmed pulmonary embolism and COVID-19 infection treated in the Intensive Care Unit of the University Hospital Medical Center “Bežanijska kosa”, Belgrade, Serbia, between April 2021 and March 2022. Predictors of the need for oxygen support were determined, while point-of-care echocardiographic parameters and various anamnestic, laboratory, and clinically significant parameters were correlated with the Pulmonary Embolism Severity Index (PESI) score. Results: More than two-thirds of patients in our study had PE symptoms present at hospital admission (68.8%). The majority of patients had segmental pulmonary embolism (48.4%), with high to very high PESI score values in 31.3% of patients. Pneumonia was present in 68.8% of the study population. The PESI score was negatively correlated with diastolic blood pressure and SaO2 at the time of PE diagnosis, LV ejection fraction, and PVAT. A positive correlation was found between the PESI score, maximum CRP, and D-dimer at the time of PTE diagnosis. A larger right ventricular diameter was associated with a greater need for oxygen support. Conclusion: Point-of-care echocardiography is a valuable tool for the risk assessment of COVID-19 patients with pulmonary embolism. Right ventricular size stood out as a significant marker of disease severity.https://www.mdpi.com/2075-4418/12/10/2380COVID-19pulmonary embolismechocardiographyPOCUS |
| spellingShingle | Slobodan Klasnja Andrea Manojlovic Viseslav Popadic Tatjana Ivankovic Nebojsa Ninkovic Nina Rajovic Maja Popovic Novica Nikolic Milica Brajkovic Aleksandra Radojevic Ratko Lasica Sasa Rajsic Zoran Todorovic Marija Brankovic Tijana Radonjic Lidija Memon Davor Mrda Natasa Milic Marija Zdravkovic Point-of-Care Echocardiographic Characteristics of COVID-19 Patients with Pulmonary Embolism Diagnostics COVID-19 pulmonary embolism echocardiography POCUS |
| title | Point-of-Care Echocardiographic Characteristics of COVID-19 Patients with Pulmonary Embolism |
| title_full | Point-of-Care Echocardiographic Characteristics of COVID-19 Patients with Pulmonary Embolism |
| title_fullStr | Point-of-Care Echocardiographic Characteristics of COVID-19 Patients with Pulmonary Embolism |
| title_full_unstemmed | Point-of-Care Echocardiographic Characteristics of COVID-19 Patients with Pulmonary Embolism |
| title_short | Point-of-Care Echocardiographic Characteristics of COVID-19 Patients with Pulmonary Embolism |
| title_sort | point of care echocardiographic characteristics of covid 19 patients with pulmonary embolism |
| topic | COVID-19 pulmonary embolism echocardiography POCUS |
| url | https://www.mdpi.com/2075-4418/12/10/2380 |
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