Brain-derived neurotrophic factor (BDNF) has direct anti-inflammatory effects on microglia

Brain-derived neurotrophic factor (BDNF) has direct anti-inflammatory effects on microglia

Microglia are the primary immunocompetent cells that protect the brain from environmental stressors, but can also be driven to release pro-inflammatory cytokines and induce a cytotoxic environment. Brain-derived neurotrophic factor (BDNF) is important for the regulation of plasticity, synapse format...

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Bibliographic Details
Main Authors: Tryston Charlton, Natalie Prowse, Ashley McFee, Noora Heiratifar, Teresa Fortin, Carley Paquette, Shawn Hayley
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Cellular Neuroscience
Subjects:
microglia
BDNF
cytokine
primary culture
neurodegeneration
neuroimmune
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2023.1188672/full

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