Effect of ginsenoside CK combined with cisplatin on the proliferation and migration of human cervical cancer HeLa cells via Ras/ERK/MAPK pathway

Effect of ginsenoside CK combined with cisplatin on the proliferation and migration of human cervical cancer HeLa cells via Ras/ERK/MAPK pathway

Ginsenoside (G-CK) has good chemo preventive and anticancer effects. However, its antimetastatic effects and underlying mechanisms on cervical cancer (CC) are still not clear. This study found that both G-CK and DDP inhibited the proliferation of HeLa cells in a concentration-dependent manner, and t...

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Bibliographic Details
Main Authors: Xiao-Li Li, Qi Yin, Wei Wang, Run-Hui Ma, Zhi-Jing Ni, Kiran Thakur, Jian-Guo Zhang, Zhao-Jun Wei
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Journal of Functional Foods
Subjects:
G-CK
Antimetastatic
EMT
RAS/MEK/ERK
PI3K/AKT
Oxidative stress
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464623000385

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