Comparison of bioactive constituents and effects on gut microbiota by in vitro fermentation between Ophicordyceps sinensis and Cordyceps militaris
Various traditional edible fungi were demonstrated to modulate gut microbiota. In this study, 1H NMR and high-throughput sequencing were used to investigate the difference of microecology modulating function between Ophicordyceps sinensis and Cordyceps militaris. The data showed that total 7 constit...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2020-05-01
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| Series: | Journal of Functional Foods |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1756464620301250 |
| _version_ | 1819292894923587584 |
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| author | Yang Ji Anxiang Su Gaoxing Ma Tianyi Tao Donglu Fang Liyan Zhao Qiuhui Hu |
| author_facet | Yang Ji Anxiang Su Gaoxing Ma Tianyi Tao Donglu Fang Liyan Zhao Qiuhui Hu |
| author_sort | Yang Ji |
| collection | DOAJ |
| description | Various traditional edible fungi were demonstrated to modulate gut microbiota. In this study, 1H NMR and high-throughput sequencing were used to investigate the difference of microecology modulating function between Ophicordyceps sinensis and Cordyceps militaris. The data showed that total 7 constituents (glucose, mannitol, trehalose, aspartate, glutamate, lysine, threonine) were selected as potential biomarkers to identify O. sinensis and C. militaris based on 1H NMR. After in vitro fermentation, both O. sinensis and C. militaris modulated gut microbiota composition, via decreasing the ratio of Firmicutes to Bacteroidetes. However, O. sinensis could significantly decreased the pH and stimulated the production of short-chain fatty acids versus C. militaris. O. sinensis also increased the relative abundance of probiotics including Phascolarctobacterium and Bifidobacterium. In general, the results suggested that O. sinensis had more positive effects on gut microbiota compared with C. militaris, which was conducive to the development of functional products of traditional edible fungi. |
| first_indexed | 2024-12-24T04:01:47Z |
| format | Article |
| id | doaj.art-cd66e56069904a939b7ac9ee3ba363b4 |
| institution | Directory Open Access Journal |
| issn | 1756-4646 |
| language | English |
| last_indexed | 2024-12-24T04:01:47Z |
| publishDate | 2020-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Functional Foods |
| spelling | doaj.art-cd66e56069904a939b7ac9ee3ba363b42022-12-21T17:16:18ZengElsevierJournal of Functional Foods1756-46462020-05-0168103901Comparison of bioactive constituents and effects on gut microbiota by in vitro fermentation between Ophicordyceps sinensis and Cordyceps militarisYang Ji0Anxiang Su1Gaoxing Ma2Tianyi Tao3Donglu Fang4Liyan Zhao5Qiuhui Hu6College of Food Science and Engineering, Nanjing University of Finance and Economics, Collaborative Innovation Center for Modern Grain Circulation and Safety, Nanjing 210023, People's Republic of ChinaCollege of Food Science and Engineering, Nanjing University of Finance and Economics, Collaborative Innovation Center for Modern Grain Circulation and Safety, Nanjing 210023, People's Republic of ChinaCollege of Food Science and Engineering, Nanjing University of Finance and Economics, Collaborative Innovation Center for Modern Grain Circulation and Safety, Nanjing 210023, People's Republic of ChinaCollege of Food Science and Engineering, Nanjing University of Finance and Economics, Collaborative Innovation Center for Modern Grain Circulation and Safety, Nanjing 210023, People's Republic of ChinaCollege of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, People's Republic of ChinaCollege of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, People's Republic of ChinaCollege of Food Science and Engineering, Nanjing University of Finance and Economics, Collaborative Innovation Center for Modern Grain Circulation and Safety, Nanjing 210023, People's Republic of China; College of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, People's Republic of China; Corresponding author at: College of Food Science and Engineering, Nanjing University of Finance and Economics, Collaborative Innovation Center for Modern Grain Circulation and Safety, Nanjing 210023, People's Republic of China.Various traditional edible fungi were demonstrated to modulate gut microbiota. In this study, 1H NMR and high-throughput sequencing were used to investigate the difference of microecology modulating function between Ophicordyceps sinensis and Cordyceps militaris. The data showed that total 7 constituents (glucose, mannitol, trehalose, aspartate, glutamate, lysine, threonine) were selected as potential biomarkers to identify O. sinensis and C. militaris based on 1H NMR. After in vitro fermentation, both O. sinensis and C. militaris modulated gut microbiota composition, via decreasing the ratio of Firmicutes to Bacteroidetes. However, O. sinensis could significantly decreased the pH and stimulated the production of short-chain fatty acids versus C. militaris. O. sinensis also increased the relative abundance of probiotics including Phascolarctobacterium and Bifidobacterium. In general, the results suggested that O. sinensis had more positive effects on gut microbiota compared with C. militaris, which was conducive to the development of functional products of traditional edible fungi.http://www.sciencedirect.com/science/article/pii/S1756464620301250Ophicordyceps sinensisCordyceps militaris1H NMR spectroscopyShort-chain fatty acidsGut microbiota |
| spellingShingle | Yang Ji Anxiang Su Gaoxing Ma Tianyi Tao Donglu Fang Liyan Zhao Qiuhui Hu Comparison of bioactive constituents and effects on gut microbiota by in vitro fermentation between Ophicordyceps sinensis and Cordyceps militaris Journal of Functional Foods Ophicordyceps sinensis Cordyceps militaris 1H NMR spectroscopy Short-chain fatty acids Gut microbiota |
| title | Comparison of bioactive constituents and effects on gut microbiota by in vitro fermentation between Ophicordyceps sinensis and Cordyceps militaris |
| title_full | Comparison of bioactive constituents and effects on gut microbiota by in vitro fermentation between Ophicordyceps sinensis and Cordyceps militaris |
| title_fullStr | Comparison of bioactive constituents and effects on gut microbiota by in vitro fermentation between Ophicordyceps sinensis and Cordyceps militaris |
| title_full_unstemmed | Comparison of bioactive constituents and effects on gut microbiota by in vitro fermentation between Ophicordyceps sinensis and Cordyceps militaris |
| title_short | Comparison of bioactive constituents and effects on gut microbiota by in vitro fermentation between Ophicordyceps sinensis and Cordyceps militaris |
| title_sort | comparison of bioactive constituents and effects on gut microbiota by in vitro fermentation between ophicordyceps sinensis and cordyceps militaris |
| topic | Ophicordyceps sinensis Cordyceps militaris 1H NMR spectroscopy Short-chain fatty acids Gut microbiota |
| url | http://www.sciencedirect.com/science/article/pii/S1756464620301250 |
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