Repetitive Neuromuscular Magnetic Stimulation for Pediatric Headache Disorders: Muscular Effects and Factors Affecting Level of Response
Repetitive neuromuscular magnetic stimulation (rNMS) for pediatric headache disorders is feasible, safe, and alleviates headache symptoms. This study assesses muscular effects and factors affecting response to rNMS. A retrospective chart review included children with headaches receiving six rNMS ses...
| Main Authors: | , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-07-01
|
| Series: | Brain Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-3425/12/7/932 |
| _version_ | 1797433795496902656 |
|---|---|
| author | Corinna Börner Jacob Staisch Magdalena Lang Ari Hauser Iris Hannibal Kristina Huß Birgit Klose Matthias F. Lechner Nico Sollmann Florian Heinen Mirjam N. Landgraf Michaela V. Bonfert |
| author_facet | Corinna Börner Jacob Staisch Magdalena Lang Ari Hauser Iris Hannibal Kristina Huß Birgit Klose Matthias F. Lechner Nico Sollmann Florian Heinen Mirjam N. Landgraf Michaela V. Bonfert |
| author_sort | Corinna Börner |
| collection | DOAJ |
| description | Repetitive neuromuscular magnetic stimulation (rNMS) for pediatric headache disorders is feasible, safe, and alleviates headache symptoms. This study assesses muscular effects and factors affecting response to rNMS. A retrospective chart review included children with headaches receiving six rNMS sessions targeting the upper trapezius muscles. Pressure pain thresholds (PPT) were measured before and after rNMS, and at 3-month follow-up (FU). Mean headache frequency, duration, and intensity within the last 3 months were documented. In 20 patients (14.1 ± 2.7 years), PPT significantly increased from pre- to post-treatment (<i>p</i> < 0.001) sustaining until FU. PPT changes significantly differed between primary headache and post-traumatic headache (PTH) (<i>p</i> = 0.019–0.026). Change in headache frequency was significantly higher in patients with than without neck pain (<i>p</i> = 0.032). A total of 60% of patients with neck pain responded to rNMS (≥25%), while 20% of patients without neck pain responded (<i>p</i> = 0.048). 60% of patients receiving rNMS twice a week were responders, while 33% of patients receiving rNMS less or more frequently responded to treatment, respectively. Alleviation of muscular hyperalgesia was demonstrated sustaining for 3 months, which was emphasized in PTH. The rNMS sessions may positively modulate headache symptoms regardless of headache diagnosis. Patients with neck pain profit explicitly well. Two rNMS sessions per week led to the highest reduction in headache frequency. |
| first_indexed | 2024-03-09T10:21:37Z |
| format | Article |
| id | doaj.art-cd67ec58da354b7b838af17e17eaa957 |
| institution | Directory Open Access Journal |
| issn | 2076-3425 |
| language | English |
| last_indexed | 2024-03-09T10:21:37Z |
| publishDate | 2022-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Brain Sciences |
| spelling | doaj.art-cd67ec58da354b7b838af17e17eaa9572023-12-01T21:57:48ZengMDPI AGBrain Sciences2076-34252022-07-0112793210.3390/brainsci12070932Repetitive Neuromuscular Magnetic Stimulation for Pediatric Headache Disorders: Muscular Effects and Factors Affecting Level of ResponseCorinna Börner0Jacob Staisch1Magdalena Lang2Ari Hauser3Iris Hannibal4Kristina Huß5Birgit Klose6Matthias F. Lechner7Nico Sollmann8Florian Heinen9Mirjam N. Landgraf10Michaela V. Bonfert11LMU Hospital, Department of Pediatrics—Dr. von Hauner Children’s Hospital, Division of Pediatric Neurology and Developmental Medicine, Ludwig-Maximilians Universität, Lindwurm Str. 4, 80337 Munich, GermanyLMU Hospital, Department of Pediatrics—Dr. von Hauner Children’s Hospital, Division of Pediatric Neurology and Developmental Medicine, Ludwig-Maximilians Universität, Lindwurm Str. 4, 80337 Munich, GermanyLMU Hospital, Department of Pediatrics—Dr. von Hauner Children’s Hospital, Division of Pediatric Neurology and Developmental Medicine, Ludwig-Maximilians Universität, Lindwurm Str. 4, 80337 Munich, GermanyLMU Hospital, Department of Pediatrics—Dr. von Hauner Children’s Hospital, Division of Pediatric Neurology and Developmental Medicine, Ludwig-Maximilians Universität, Lindwurm Str. 4, 80337 Munich, GermanyLMU Hospital, Department of Pediatrics—Dr. von Hauner Children’s Hospital, Division of Pediatric Neurology and Developmental Medicine, Ludwig-Maximilians Universität, Lindwurm Str. 4, 80337 Munich, GermanyLMU Hospital, Department of Pediatrics—Dr. von Hauner Children’s Hospital, Division of Pediatric Neurology and Developmental Medicine, Ludwig-Maximilians Universität, Lindwurm Str. 4, 80337 Munich, GermanyLMU Hospital, Department of Pediatrics—Dr. von Hauner Children’s Hospital, Division of Pediatric Neurology and Developmental Medicine, Ludwig-Maximilians Universität, Lindwurm Str. 4, 80337 Munich, GermanyLMU Hospital, Department of Pediatrics—Dr. von Hauner Children’s Hospital, Division of Pediatric Neurology and Developmental Medicine, Ludwig-Maximilians Universität, Lindwurm Str. 4, 80337 Munich, GermanyDepartment of Diagnostic and Interventional Neuroradiology, School of Medicine, Klinikum Rechts der Isar, Technical University of Munich, Ismaninger Str. 22, 81675 Munich, GermanyLMU Hospital, Department of Pediatrics—Dr. von Hauner Children’s Hospital, Division of Pediatric Neurology and Developmental Medicine, Ludwig-Maximilians Universität, Lindwurm Str. 4, 80337 Munich, GermanyLMU Hospital, Department of Pediatrics—Dr. von Hauner Children’s Hospital, Division of Pediatric Neurology and Developmental Medicine, Ludwig-Maximilians Universität, Lindwurm Str. 4, 80337 Munich, GermanyLMU Hospital, Department of Pediatrics—Dr. von Hauner Children’s Hospital, Division of Pediatric Neurology and Developmental Medicine, Ludwig-Maximilians Universität, Lindwurm Str. 4, 80337 Munich, GermanyRepetitive neuromuscular magnetic stimulation (rNMS) for pediatric headache disorders is feasible, safe, and alleviates headache symptoms. This study assesses muscular effects and factors affecting response to rNMS. A retrospective chart review included children with headaches receiving six rNMS sessions targeting the upper trapezius muscles. Pressure pain thresholds (PPT) were measured before and after rNMS, and at 3-month follow-up (FU). Mean headache frequency, duration, and intensity within the last 3 months were documented. In 20 patients (14.1 ± 2.7 years), PPT significantly increased from pre- to post-treatment (<i>p</i> < 0.001) sustaining until FU. PPT changes significantly differed between primary headache and post-traumatic headache (PTH) (<i>p</i> = 0.019–0.026). Change in headache frequency was significantly higher in patients with than without neck pain (<i>p</i> = 0.032). A total of 60% of patients with neck pain responded to rNMS (≥25%), while 20% of patients without neck pain responded (<i>p</i> = 0.048). 60% of patients receiving rNMS twice a week were responders, while 33% of patients receiving rNMS less or more frequently responded to treatment, respectively. Alleviation of muscular hyperalgesia was demonstrated sustaining for 3 months, which was emphasized in PTH. The rNMS sessions may positively modulate headache symptoms regardless of headache diagnosis. Patients with neck pain profit explicitly well. Two rNMS sessions per week led to the highest reduction in headache frequency.https://www.mdpi.com/2076-3425/12/7/932migrainetension-type headachepost-traumatic headacheneuromodulationneurostimulation |
| spellingShingle | Corinna Börner Jacob Staisch Magdalena Lang Ari Hauser Iris Hannibal Kristina Huß Birgit Klose Matthias F. Lechner Nico Sollmann Florian Heinen Mirjam N. Landgraf Michaela V. Bonfert Repetitive Neuromuscular Magnetic Stimulation for Pediatric Headache Disorders: Muscular Effects and Factors Affecting Level of Response Brain Sciences migraine tension-type headache post-traumatic headache neuromodulation neurostimulation |
| title | Repetitive Neuromuscular Magnetic Stimulation for Pediatric Headache Disorders: Muscular Effects and Factors Affecting Level of Response |
| title_full | Repetitive Neuromuscular Magnetic Stimulation for Pediatric Headache Disorders: Muscular Effects and Factors Affecting Level of Response |
| title_fullStr | Repetitive Neuromuscular Magnetic Stimulation for Pediatric Headache Disorders: Muscular Effects and Factors Affecting Level of Response |
| title_full_unstemmed | Repetitive Neuromuscular Magnetic Stimulation for Pediatric Headache Disorders: Muscular Effects and Factors Affecting Level of Response |
| title_short | Repetitive Neuromuscular Magnetic Stimulation for Pediatric Headache Disorders: Muscular Effects and Factors Affecting Level of Response |
| title_sort | repetitive neuromuscular magnetic stimulation for pediatric headache disorders muscular effects and factors affecting level of response |
| topic | migraine tension-type headache post-traumatic headache neuromodulation neurostimulation |
| url | https://www.mdpi.com/2076-3425/12/7/932 |
| work_keys_str_mv | AT corinnaborner repetitiveneuromuscularmagneticstimulationforpediatricheadachedisordersmusculareffectsandfactorsaffectinglevelofresponse AT jacobstaisch repetitiveneuromuscularmagneticstimulationforpediatricheadachedisordersmusculareffectsandfactorsaffectinglevelofresponse AT magdalenalang repetitiveneuromuscularmagneticstimulationforpediatricheadachedisordersmusculareffectsandfactorsaffectinglevelofresponse AT arihauser repetitiveneuromuscularmagneticstimulationforpediatricheadachedisordersmusculareffectsandfactorsaffectinglevelofresponse AT irishannibal repetitiveneuromuscularmagneticstimulationforpediatricheadachedisordersmusculareffectsandfactorsaffectinglevelofresponse AT kristinahuß repetitiveneuromuscularmagneticstimulationforpediatricheadachedisordersmusculareffectsandfactorsaffectinglevelofresponse AT birgitklose repetitiveneuromuscularmagneticstimulationforpediatricheadachedisordersmusculareffectsandfactorsaffectinglevelofresponse AT matthiasflechner repetitiveneuromuscularmagneticstimulationforpediatricheadachedisordersmusculareffectsandfactorsaffectinglevelofresponse AT nicosollmann repetitiveneuromuscularmagneticstimulationforpediatricheadachedisordersmusculareffectsandfactorsaffectinglevelofresponse AT florianheinen repetitiveneuromuscularmagneticstimulationforpediatricheadachedisordersmusculareffectsandfactorsaffectinglevelofresponse AT mirjamnlandgraf repetitiveneuromuscularmagneticstimulationforpediatricheadachedisordersmusculareffectsandfactorsaffectinglevelofresponse AT michaelavbonfert repetitiveneuromuscularmagneticstimulationforpediatricheadachedisordersmusculareffectsandfactorsaffectinglevelofresponse |