Ketamine affects the integration of developmentally generated granule neurons in the adult stage

Ketamine affects the integration of developmentally generated granule neurons in the adult stage

Abstract Background Ketamine has been reported to cause neonatal neurotoxicity in a variety of developing animal models. Various studies have been conducted to study the mechanism of neurotoxicity for general anesthetic use during the neonatal period. Previous experiments have suggested that develop...

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Bibliographic Details
Main Authors: Zhanqiang Zhao, Bing Li, Yuqing Wu, Xujun Chen, Yan Guo, Yang Shen, He Huang
Format: Article
Language:English
Published: BMC 2019-12-01
Series:BMC Neuroscience
Subjects:
Ketamine
Dentate gyrus
Functional integration
Neural circuits
Morris water maze
Learning
Online Access:https://doi.org/10.1186/s12868-019-0542-4

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