Targeted and whole-genome sequencing reveal a north-south divide in P. falciparum drug resistance markers and genetic structure in Mozambique

Abstract Mozambique is one of the four African countries which account for over half of all malaria deaths worldwide, yet little is known about the parasite genetic structure in that country. We performed P. falciparum amplicon and whole genome sequencing on 2251 malaria-infected blood samples colle...

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Bibliographic Details
Main Authors: Clemente da Silva, Simone Boene, Debayan Datta, Eduard Rovira-Vallbona, Andrés Aranda-Díaz, Pau Cisteró, Nicholas Hathaway, Sofonias Tessema, Arlindo Chidimatembue, Glória Matambisso, Abel Nhama, Eusebio Macete, Arnau Pujol, Lidia Nhamussua, Beatriz Galatas, Caterina Guinovart, Sónia Enosse, Eva De Carvalho, Eric Rogier, Mateusz M. Plucinski, James Colborn, Rose Zulliger, Abuchahama Saifodine, Pedro L. Alonso, Baltazar Candrinho, Bryan Greenhouse, Pedro Aide, Francisco Saute, Alfredo Mayor
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-04997-7

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