Painful angiomyxoid tumor in a failed renal allograft presenting as post-transplant lymphoproliferative disorder
Introduction: There exist few reports of de novo tumors involving an allograft kidney, and to the best of our knowledge there are only two previous reports of angiomyxoma Case Presentation: A 53-year-old Caucasian male with end-stage renal disease (ESRD) on hemodialysis (HD) secondary to malakoplaki...
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| Format: | Article |
| Language: | English |
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Society of Diabetic Nephropathy Prevention
2020-04-01
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| Series: | Journal of Nephropathology |
| Subjects: | |
| Online Access: | https://nephropathol.com/PDF/jnp-9-e20.pdf |
| _version_ | 1797828003744448512 |
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| author | Paulette Cutruzzula Dreher Jessica M. Fazendin Kelly Lurz Daniel C. Edwards Stephen Guy Melanie Amster |
| author_facet | Paulette Cutruzzula Dreher Jessica M. Fazendin Kelly Lurz Daniel C. Edwards Stephen Guy Melanie Amster |
| author_sort | Paulette Cutruzzula Dreher |
| collection | DOAJ |
| description | Introduction: There exist few reports of de novo tumors involving an allograft kidney, and to the best of our knowledge there are only two previous reports of angiomyxoma Case Presentation: A 53-year-old Caucasian male with end-stage renal disease (ESRD) on hemodialysis (HD) secondary to malakoplakia with three failed prior renal transplants presented for repeat transplant evaluation. Imaging demonstrated a mass of the transplanted kidney suggestive of posttransplant lymphoproliferative disease (PTLPD). A biopsy was obtained revealing a predominance of myxoid material. The patient became increasingly symptomatic from the mass and underwent a palliative right transplant nephrectomy. Final pathology revealed angiomyxoid tumor. Conclusions: Angiomyxomas are asymptomatic, appear as PTLD on imaging and should be considered in the differential diagnosis of masses occurring in renal transplant allografts. |
| first_indexed | 2024-04-09T12:57:30Z |
| format | Article |
| id | doaj.art-cd6b8fc6f3344366802fde73aa1f8681 |
| institution | Directory Open Access Journal |
| issn | 2251-8363 2251-8819 |
| language | English |
| last_indexed | 2024-04-09T12:57:30Z |
| publishDate | 2020-04-01 |
| publisher | Society of Diabetic Nephropathy Prevention |
| record_format | Article |
| series | Journal of Nephropathology |
| spelling | doaj.art-cd6b8fc6f3344366802fde73aa1f86812023-05-13T11:26:50ZengSociety of Diabetic Nephropathy PreventionJournal of Nephropathology2251-83632251-88192020-04-0192e20e2010.34172/jnp.2020.20jnp-4787Painful angiomyxoid tumor in a failed renal allograft presenting as post-transplant lymphoproliferative disorderPaulette Cutruzzula Dreher0Jessica M. Fazendin1Kelly Lurz2Daniel C. Edwards3Stephen Guy4Melanie Amster5Department of Urology, Hahnemann University Hospital, Philadelphia, PA, USADepartment of General Surgery, Drexel University College of Medicine, Philadelphia, PA, USADepartment of Urology, Hahnemann University Hospital, Philadelphia, PA, USADepartment of Urology, Hahnemann University Hospital, Philadelphia, PA, USADepartment of Urology, Hahnemann University Hospital, Philadelphia, PA, USADepartment of Urology, Hahnemann University Hospital, Philadelphia, PA, USAIntroduction: There exist few reports of de novo tumors involving an allograft kidney, and to the best of our knowledge there are only two previous reports of angiomyxoma Case Presentation: A 53-year-old Caucasian male with end-stage renal disease (ESRD) on hemodialysis (HD) secondary to malakoplakia with three failed prior renal transplants presented for repeat transplant evaluation. Imaging demonstrated a mass of the transplanted kidney suggestive of posttransplant lymphoproliferative disease (PTLPD). A biopsy was obtained revealing a predominance of myxoid material. The patient became increasingly symptomatic from the mass and underwent a palliative right transplant nephrectomy. Final pathology revealed angiomyxoid tumor. Conclusions: Angiomyxomas are asymptomatic, appear as PTLD on imaging and should be considered in the differential diagnosis of masses occurring in renal transplant allografts.https://nephropathol.com/PDF/jnp-9-e20.pdfangiomyxoid tumorrenal transplantpost-transplant lymphoproliferative diseasemalakoplakia |
| spellingShingle | Paulette Cutruzzula Dreher Jessica M. Fazendin Kelly Lurz Daniel C. Edwards Stephen Guy Melanie Amster Painful angiomyxoid tumor in a failed renal allograft presenting as post-transplant lymphoproliferative disorder Journal of Nephropathology angiomyxoid tumor renal transplant post-transplant lymphoproliferative disease malakoplakia |
| title | Painful angiomyxoid tumor in a failed renal allograft presenting as post-transplant lymphoproliferative disorder |
| title_full | Painful angiomyxoid tumor in a failed renal allograft presenting as post-transplant lymphoproliferative disorder |
| title_fullStr | Painful angiomyxoid tumor in a failed renal allograft presenting as post-transplant lymphoproliferative disorder |
| title_full_unstemmed | Painful angiomyxoid tumor in a failed renal allograft presenting as post-transplant lymphoproliferative disorder |
| title_short | Painful angiomyxoid tumor in a failed renal allograft presenting as post-transplant lymphoproliferative disorder |
| title_sort | painful angiomyxoid tumor in a failed renal allograft presenting as post transplant lymphoproliferative disorder |
| topic | angiomyxoid tumor renal transplant post-transplant lymphoproliferative disease malakoplakia |
| url | https://nephropathol.com/PDF/jnp-9-e20.pdf |
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