Burden of tuberculosis and TB/HIV co-infection in Dushanbe
The objective of the study: to determine the burden of tuberculosis with concurrent HIV infection in Dushanbe and the prevalence of multiple drug resistant tuberculosis, to assess the treatment efficacy of drug susceptible and drug resistant tuberculosis depending on the HIV status of patients.Subje...
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| Format: | Article |
| Language: | Russian |
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New Terra Publishing House
2021-03-01
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| Series: | Туберкулез и болезни лёгких |
| Subjects: | |
| Online Access: | https://www.tibl-journal.com/jour/article/view/1510 |
| _version_ | 1826563012350181376 |
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| author | B. P. Pirmakhmadzoda Z. Kh. Tilloeva Kh. S. Sharifzoda O. Ya. Kabirov K. A. Imomnazarova S. M. Odinaeva |
| author_facet | B. P. Pirmakhmadzoda Z. Kh. Tilloeva Kh. S. Sharifzoda O. Ya. Kabirov K. A. Imomnazarova S. M. Odinaeva |
| author_sort | B. P. Pirmakhmadzoda |
| collection | DOAJ |
| description | The objective of the study: to determine the burden of tuberculosis with concurrent HIV infection in Dushanbe and the prevalence of multiple drug resistant tuberculosis, to assess the treatment efficacy of drug susceptible and drug resistant tuberculosis depending on the HIV status of patients.Subjects: A cohort retrospective study was carried out assessing results of examination and treatment of all patients (1,838 people) registered for tuberculosis treatment from 01.06.2016 to 25.12.2019 in Dushanbe.Results. Among new tuberculosis cases, MDR is more often registered in HIV positive patients versus HIV negative patients (OR 2.3, 95% CI 1.1-4.9, p = 0.03). The chances of successful treatment of tuberculosis in HIV negative patients were higher versus HIV positive patients as well as in drug susceptible tuberculosis (OR 4.7, 95% CI 3.1-7.4; p < 0.000) versus drug resistant tuberculosis (OR 2.5, 95% CI 1.1-75.7; p = 0.03). The chances of tuberculosis cure did not differ statistically significantly among patients with different HIV status for both drug resistant and drug susceptible tuberculosis. |
| first_indexed | 2024-03-12T18:41:10Z |
| format | Article |
| id | doaj.art-cd6c2a64f6794696a68dc8e48c320f12 |
| institution | Directory Open Access Journal |
| issn | 2075-1230 2542-1506 |
| language | Russian |
| last_indexed | 2025-03-14T09:57:12Z |
| publishDate | 2021-03-01 |
| publisher | New Terra Publishing House |
| record_format | Article |
| series | Туберкулез и болезни лёгких |
| spelling | doaj.art-cd6c2a64f6794696a68dc8e48c320f122025-03-02T11:22:33ZrusNew Terra Publishing HouseТуберкулез и болезни лёгких2075-12302542-15062021-03-01992404410.21292/2075-1230-2021-99-2-40-441507Burden of tuberculosis and TB/HIV co-infection in DushanbeB. P. Pirmakhmadzoda0Z. Kh. Tilloeva1Kh. S. Sharifzoda2O. Ya. Kabirov3K. A. Imomnazarova4S. M. Odinaeva5City Center for Population Protection from TuberculosisCity Center for Population Protection from TuberculosisDushanbe City Health AdministrationNational Reference Laboratory, National Center of Tuberculosis, Lung Diseases and Thoracic SurgeryCity Center for Population Protection from TuberculosisCity Center for Population Protection from TuberculosisThe objective of the study: to determine the burden of tuberculosis with concurrent HIV infection in Dushanbe and the prevalence of multiple drug resistant tuberculosis, to assess the treatment efficacy of drug susceptible and drug resistant tuberculosis depending on the HIV status of patients.Subjects: A cohort retrospective study was carried out assessing results of examination and treatment of all patients (1,838 people) registered for tuberculosis treatment from 01.06.2016 to 25.12.2019 in Dushanbe.Results. Among new tuberculosis cases, MDR is more often registered in HIV positive patients versus HIV negative patients (OR 2.3, 95% CI 1.1-4.9, p = 0.03). The chances of successful treatment of tuberculosis in HIV negative patients were higher versus HIV positive patients as well as in drug susceptible tuberculosis (OR 4.7, 95% CI 3.1-7.4; p < 0.000) versus drug resistant tuberculosis (OR 2.5, 95% CI 1.1-75.7; p = 0.03). The chances of tuberculosis cure did not differ statistically significantly among patients with different HIV status for both drug resistant and drug susceptible tuberculosis.https://www.tibl-journal.com/jour/article/view/1510tuberculosisdrug susceptibility of mycobacterium tuberculosishiv statustreatment |
| spellingShingle | B. P. Pirmakhmadzoda Z. Kh. Tilloeva Kh. S. Sharifzoda O. Ya. Kabirov K. A. Imomnazarova S. M. Odinaeva Burden of tuberculosis and TB/HIV co-infection in Dushanbe Туберкулез и болезни лёгких tuberculosis drug susceptibility of mycobacterium tuberculosis hiv status treatment |
| title | Burden of tuberculosis and TB/HIV co-infection in Dushanbe |
| title_full | Burden of tuberculosis and TB/HIV co-infection in Dushanbe |
| title_fullStr | Burden of tuberculosis and TB/HIV co-infection in Dushanbe |
| title_full_unstemmed | Burden of tuberculosis and TB/HIV co-infection in Dushanbe |
| title_short | Burden of tuberculosis and TB/HIV co-infection in Dushanbe |
| title_sort | burden of tuberculosis and tb hiv co infection in dushanbe |
| topic | tuberculosis drug susceptibility of mycobacterium tuberculosis hiv status treatment |
| url | https://www.tibl-journal.com/jour/article/view/1510 |
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