Short-chain 3-hydroxyacyl-coenzyme A dehydrogenase associates with a protein super-complex integrating multiple metabolic pathways.

Short-chain 3-hydroxyacyl-coenzyme A dehydrogenase associates with a protein super-complex integrating multiple metabolic pathways.

Proteins involved in mitochondrial metabolic pathways engage in functionally relevant multi-enzyme complexes. We previously described an interaction between short-chain 3-hydroxyacyl-coenzyme A dehydrogenase (SCHAD) and glutamate dehydrogenase (GDH) explaining the clinical phenotype of hyperinsulini...

Full description

Bibliographic Details
Main Authors:	Srinivas B Narayan, Stephen R Master, Anthony N Sireci, Charlene Bierl, Paige E Stanley, Changhong Li, Charles A Stanley, Michael J Bennett
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2012-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC3322157?pdf=render

Similar Items

Genetic pathogenesis, diagnosis, and treatment of short-chain 3-hydroxyacyl-coenzyme A dehydrogenase hyperinsulinism
by: Wei Zhang, et al.
Published: (2021-11-01)

Role of short-chain hydroxyacyl CoA dehydrogenases in SCHAD deficiency.
by: Filling, C, et al.
Published: (2008)

Progress of the effect of hydroxyacyl- coenzyme A dehydrogenase in cancer development and its mechanism
by: WU Guojia, ZHAI Shujie, SUN Xiao, HUANG Yiran, LI Yongmei, SUN Li
Published: (2024-01-01)

A Rare Case with Short Chain Hydroxyacyl-CoA Dehydrogenase Deficiency (SCHAD) with Symptom of Cardiac Involvement
by: M Mohammadi, et al.
Published: (2013-07-01)

Management of pregnancy in a patient with long‐chain 3‐hydroxyacyl CoA dehydrogenase deficiency
by: Loai A. Shakerdi, et al.
Published: (2022-07-01)

Follow-up and multimodal imaging in long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency
by: Glenda Espinosa-Barberi, et al.
Published: (2018-10-01)

Short-chain L-3-hydroxyacyl-CoA dehydrogenase: A novel vital oncogene or tumor suppressor gene in cancers
by: He Fang, et al.
Published: (2022-10-01)

Coenzyme-based functional assignments of short-chain dehydrogenases/reductases (SDRs).
by: Persson, B, et al.
Published: (2003)

Ophthalmic Symptoms of Long-Chain 3-Hydroxyacyl-CoA Dehydrogenase Deficiency: A Report of Three Cases
by: Natalia Lange, et al.
Published: (2024-04-01)

New Acylcarnitine Ratio as a Reliable Indicator of Long-Chain 3-Hydroxyacyl-CoA Dehydrogenase Deficiency
by: Galina V. Baydakova, et al.
Published: (2023-08-01)

Leptospiral 3-hydroxyacyl-CoA dehydrogenase as an early urinary biomarker of leptospirosis
by: Claudia Toma, et al.
Published: (2018-04-01)

Optical coherence tomography angiography of choroidal neovascularization in long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency (LCHADD)
by: Nida Wongchaisuwat, et al.
Published: (2023-12-01)

Very long-chain acyl-coenzyme A dehydrogenase deficiency
by: A. V. Degtyareva, et al.
Published: (2016-03-01)

Molecular characterization and immune protection of the 3-hydroxyacyl-CoA dehydrogenase gene in Echinococcus granulosus
by: Jinwen Xian, et al.
Published: (2021-09-01)

Fatal pitfalls in newborn screening for mitochondrial trifunctional protein (MTP)/long-chain 3-Hydroxyacyl-CoA dehydrogenase (LCHAD) deficiency
by: Amelie S. Lotz-Havla, et al.
Published: (2018-07-01)

Fatal COVID‐19 infection in a patient with long‐chain 3‐hydroxyacyl‐CoA dehydrogenase deficiency: A case report
by: Parith Wongkittichote, et al.
Published: (2020-11-01)

Enoyl-CoA hydratase/3-hydroxyacyl CoA dehydrogenase is essential for the production of DHA in zebrafish
by: Gang Yang, et al.
Published: (2023-03-01)

Leucine-sensitive hyperinsulinaemic hypoglycaemia in patients with loss of function mutations in 3-Hydroxyacyl-CoA Dehydrogenase
by: Heslegrave Amanda J, et al.
Published: (2012-05-01)

Clinical phenotype and gene mutation of short-chain acyl-coenzyme A dehydrogenase deficiency in a Chinese family
by: Xin-na JI, et al.
Published: (2018-08-01)

Outcomes and genotype correlations in patients with mitochondrial trifunctional protein or isolated long chain 3-hydroxyacyl-CoA dehydrogenase deficiency enrolled in the IBEM-IS database
by: Chelsey Chaehee Lim, et al.
Published: (2022-09-01)

The effect of short/branched chain acyl-coenzyme A dehydrogenase gene on triglyceride synthesis of bovine mammary epithelial cells
by: P. Jiang, et al.
Published: (2018-03-01)

Binding of coenzymes to yeast alcohol dehydrogenase
by: VLADIMIR LESKOVAC, et al.
Published: (2010-02-01)

Impact of Newborn Screening and Early Dietary Management on Clinical Outcome of Patients with Long Chain 3-Hydroxyacyl-CoA Dehydrogenase Deficiency and Medium Chain Acyl-CoA Dehydrogenase Deficiency—A Retrospective Nationwide Study
by: Kristina Rücklová, et al.
Published: (2021-08-01)

Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta gene as a tumour suppressor in stomach adenocarcinoma
by: Yun Li, et al.
Published: (2022-11-01)

β-hydroxyacyl-CoA-dehydrogenase activity differentiates unfrozen from frozen-thawed Yellowfin tuna (Thunnus albacares)
by: Cristian Bernardi, et al.
Published: (2019-10-01)

A G1528C Hadha knock-in mouse model recapitulates aspects of human clinical phenotypes for long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency
by: Garen Gaston, et al.
Published: (2023-08-01)

Leptospiral 3-hydroxyacyl-CoA dehydrogenase as an early urinary biomarker of leptospirosis in a Sri Lankan setting – Interim results
by: A. K. U. I. Karunadasa, et al.
Published: (2021-12-01)

Rhabdomyolysis as a presenting manifestation of very long-chain acyl-coenzyme A dehydrogenase deficiency
by: Sara Freitas Oliveira, et al.
Published: (2013-08-01)

A case of lipid metabolic myopathy: very-long-chain acyl-coenzyme A dehydrogenase deficiency
by: Miao-miao HOU, et al.
Published: (2013-02-01)

Short-chain dehydrogenases/reductases (SDRs).
by: Kallberg, Y, et al.
Published: (2002)

Binding of amyloid beta-peptide to mitochondrial hydroxyacyl-CoA dehydrogenase (ERAB): regulation of an SDR enzyme activity with implications for apoptosis in Alzheimer's disease.
by: Oppermann, U, et al.
Published: (1999)

Transcriptomic Analysis of Short/Branched-Chain Acyl-Coenzyme a Dehydrogenase Knocked Out bMECs Revealed Its Regulatory Effect on Lipid Metabolism
by: Ping Jiang, et al.
Published: (2021-09-01)

Suppression of estrogen-related receptor α and medium-chain acyl-coenzyme A dehydrogenase in the acute-phase response
by: Min Sun Kim, et al.
Published: (2005-10-01)

High prevalence of carriers of variant c.1528G>C of HADHA gene causing long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency (LCHADD) in the population of adult Kashubians from North Poland.
by: Bogusław Nedoszytko, et al.
Published: (2017-01-01)

Isomerization of an enzyme-coenzyme complex in yeast alcohol dehydrogenase-catalyzed reactions
by: DRAGINJA PERICIN, et al.
Published: (2003-02-01)

Isomerization of an enzyme-coenzyme complex in yeast alcohol dehydrogenase-catalysed reactions
by: Leskovac Vladimir M., et al.
Published: (2003-01-01)

High coenzyme affinity chimeric amine dehydrogenase based on domain engineering
by: Jialin Li, et al.
Published: (2022-03-01)

An Altered Sphingolipid Profile as a Risk Factor for Progressive Neurodegeneration in Long-Chain 3-Hydroxyacyl-CoA Deficiency (LCHADD)
by: Sara Tucci
Published: (2022-06-01)

Enantiocomplementary Yarrowia lipolytica Oxidoreductases: Alcohol Dehydrogenase 2 and Short Chain Dehydrogenase/Reductase
by: Margit Winkler, et al.
Published: (2013-08-01)

Salinomycin biosynthesis reversely regulates the β‐oxidation pathway in Streptomyces albus by carrying a 3‐hydroxyacyl‐CoA dehydrogenase gene in its biosynthetic gene cluster
by: Jiaxiu Wei, et al.
Published: (2022-12-01)