Avoidance of stochastic RNA interactions can be harnessed to control protein expression levels in bacteria and archaea

Avoidance of stochastic RNA interactions can be harnessed to control protein expression levels in bacteria and archaea

A critical assumption of gene expression analysis is that mRNA abundances broadly correlate with protein abundance, but these two are often imperfectly correlated. Some of the discrepancy can be accounted for by two important mRNA features: codon usage and mRNA secondary structure. We present a new...

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Bibliographic Details
Main Authors: Sinan Uğur Umu, Anthony M Poole, Renwick CJ Dobson, Paul P Gardner
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-09-01
Series:eLife
Subjects:
ncRNA
Archaea
bacteria
gene expression
bioinformatics
Online Access:https://elifesciences.org/articles/13479

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