Epigenome-wide methylation and progression to high-grade cervical intraepithelial neoplasia (CIN2+): a prospective cohort study in the United States

Epigenome-wide methylation and progression to high-grade cervical intraepithelial neoplasia (CIN2+): a prospective cohort study in the United States

Abstract Background Methylation levels may be associated with and serve as markers to predict risk of progression of precancerous cervical lesions. We conducted an epigenome-wide association study (EWAS) of CpG methylation and progression to high-grade cervical intraepithelial neoplasia (CIN2 +) fol...

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Bibliographic Details
Main Authors: Alexandra Bukowski, Cathrine Hoyo, Nadja A. Vielot, Misa Graff, Michael R. Kosorok, Wendy R. Brewster, Rachel L. Maguire, Susan K. Murphy, Belinda Nedjai, Efthymios Ladoukakis, Kari E. North, Jennifer S. Smith
Format: Article
Language:English
Published: BMC 2023-11-01
Series:BMC Cancer
Subjects:
Cervical cancer
Cancer surveillance and screening
DNA methylation
Epigenomics
Epigenetics
Cancer risk
Online Access:https://doi.org/10.1186/s12885-023-11518-6

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