Optimizing Soluble Cues for Salivary Gland Tissue Mimetics Using a Design of Experiments (DoE) Approach
The development of therapies to prevent or treat salivary gland dysfunction has been limited by a lack of functional in vitro models. Specifically, critical markers of salivary gland secretory phenotype downregulate rapidly ex vivo. Here, we utilize a salivary gland tissue chip model to conduct a de...
Main Authors: | Lindsay R. Piraino, Danielle S. W. Benoit, Lisa A. DeLouise |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-06-01
|
Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/11/12/1962 |
Similar Items
-
Salivary Gland Tissue Engineering Approaches: State of the Art and Future Directions
by: Lindsay R. Piraino, et al.
Published: (2021-07-01) -
Emerging organoid-based platforms to study salivary gland hypofunction
by: Yoojin Seo, et al.
Published: (2022-03-01) -
Immortalization of Salivary Gland Epithelial Cells of Xerostomic Patients: Establishment and Characterization of Novel Cell Lines
by: Braxton D. Noll, et al.
Published: (2020-11-01) -
Salivary gland disorders and diseases /
by: Bradley, Patrick J., 1949-, et al.
Published: (2011) -
The integrated stress response is activated in the salivary glands of Sjögren’s syndrome patients
by: Patricia Carvajal, et al.
Published: (2023-03-01)