The Synergistic Effect of Microwave Radiation and Hypergravity on Rats and the Intervention Effect of Rana Sylvatica Le Conte Oil

Aim: The phenomena of hypergravity and microwave radiation are widespread, which cause more and more concern for the hazards to human health. The aim of this study was to investigate the synergistic effect of microwave radiation and hypergravity on rats and observe the protective effect of Rana sylv...

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Main Authors: Wei Sun, Yudan Yang, Hongmei Yu, Luowei Wang, Su Pan
Format: Article
Language:English
Published: SAGE Publishing 2017-06-01
Series:Dose-Response
Online Access:https://doi.org/10.1177/1559325817711511
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author Wei Sun
Yudan Yang
Hongmei Yu
Luowei Wang
Su Pan
author_facet Wei Sun
Yudan Yang
Hongmei Yu
Luowei Wang
Su Pan
author_sort Wei Sun
collection DOAJ
description Aim: The phenomena of hypergravity and microwave radiation are widespread, which cause more and more concern for the hazards to human health. The aim of this study was to investigate the synergistic effect of microwave radiation and hypergravity on rats and observe the protective effect of Rana sylvatica Le conte oil. Methods: Rats were exposed to microwave radiation and hypergravity, and the rat weight, the climbing pole height, serum enzyme activities, blood urea nitrogen concentration, and total antioxidant capacity were detected. Results: The climbing pole height, the activities of choline acetyl transferase and cholinesterase, and the total antioxidant capacity decreased, whereas the activities of alanine aminotransferase, aspartate aminotransferase, areatine kinase, isocitric dehydrogenase, hydroxybutyrate dehydrogenase, and the blood urea nitrogen concentration increased in the hypergravity irradiation group as compared with the others. Conclusion: These results imply that the motion and nervous system of rats might be affected critically by the synergistic effect of microwave radiation and hypergravity, and it causes damage to most rat organs, such as the bone, skeletal muscle, liver, heart, and kidney, and the antioxidant effect is also damaged, while the injury resulted from it could be protected by Rana sylvatica Le conte oil.
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spelling doaj.art-cd7a6ccf885d476ba41a700ec13a0ff02022-12-21T17:59:51ZengSAGE PublishingDose-Response1559-32582017-06-011510.1177/1559325817711511The Synergistic Effect of Microwave Radiation and Hypergravity on Rats and the Intervention Effect of Rana Sylvatica Le Conte OilWei Sun0Yudan Yang1Hongmei Yu2Luowei Wang3Su Pan4 Department of Molecular Biology, College of Basic Medical Sciences, Jilin University, Changchun Jilin, China China-Japan Union Hospital of Jilin University, Changchun, People’s Republic of China China-Japan Union Hospital of Jilin University, Changchun, People’s Republic of China Department of Molecular Biology, College of Basic Medical Sciences, Jilin University, Changchun Jilin, China Department of Orthopedics, the Second Hospital of Jilin University, Changchun, People’s Republic of ChinaAim: The phenomena of hypergravity and microwave radiation are widespread, which cause more and more concern for the hazards to human health. The aim of this study was to investigate the synergistic effect of microwave radiation and hypergravity on rats and observe the protective effect of Rana sylvatica Le conte oil. Methods: Rats were exposed to microwave radiation and hypergravity, and the rat weight, the climbing pole height, serum enzyme activities, blood urea nitrogen concentration, and total antioxidant capacity were detected. Results: The climbing pole height, the activities of choline acetyl transferase and cholinesterase, and the total antioxidant capacity decreased, whereas the activities of alanine aminotransferase, aspartate aminotransferase, areatine kinase, isocitric dehydrogenase, hydroxybutyrate dehydrogenase, and the blood urea nitrogen concentration increased in the hypergravity irradiation group as compared with the others. Conclusion: These results imply that the motion and nervous system of rats might be affected critically by the synergistic effect of microwave radiation and hypergravity, and it causes damage to most rat organs, such as the bone, skeletal muscle, liver, heart, and kidney, and the antioxidant effect is also damaged, while the injury resulted from it could be protected by Rana sylvatica Le conte oil.https://doi.org/10.1177/1559325817711511
spellingShingle Wei Sun
Yudan Yang
Hongmei Yu
Luowei Wang
Su Pan
The Synergistic Effect of Microwave Radiation and Hypergravity on Rats and the Intervention Effect of Rana Sylvatica Le Conte Oil
Dose-Response
title The Synergistic Effect of Microwave Radiation and Hypergravity on Rats and the Intervention Effect of Rana Sylvatica Le Conte Oil
title_full The Synergistic Effect of Microwave Radiation and Hypergravity on Rats and the Intervention Effect of Rana Sylvatica Le Conte Oil
title_fullStr The Synergistic Effect of Microwave Radiation and Hypergravity on Rats and the Intervention Effect of Rana Sylvatica Le Conte Oil
title_full_unstemmed The Synergistic Effect of Microwave Radiation and Hypergravity on Rats and the Intervention Effect of Rana Sylvatica Le Conte Oil
title_short The Synergistic Effect of Microwave Radiation and Hypergravity on Rats and the Intervention Effect of Rana Sylvatica Le Conte Oil
title_sort synergistic effect of microwave radiation and hypergravity on rats and the intervention effect of rana sylvatica le conte oil
url https://doi.org/10.1177/1559325817711511
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