Polymorphisms in Plasmodium vivax antifolate resistance markers in Afghanistan between 2007 and 2017

Polymorphisms in Plasmodium vivax antifolate resistance markers in Afghanistan between 2007 and 2017

Abstract Background Plasmodium vivax is the predominant Plasmodium species in Afghanistan. National guidelines recommend the combination of chloroquine and primaquine (CQ-PQ) for radical treatment of P. vivax malaria. Artesunate in combination with the antifolates sulfadoxine-pyrimethamine (SP) has...

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Bibliographic Details
Main Authors:	Kasama Rakmark, Ghulam R. Awab, Jureeporn Duanguppama, Usa Boonyuen, Arjen M. Dondorp, Mallika Imwong
Format:	Article
Language:	English
Published:	BMC 2020-07-01
Series:	Malaria Journal
Subjects:	Plasmodium vivax Antifolate resistance Dihydrofolate reductase (DHFR) and dihydropteroate synthase (DHPS) Afghanistan
Online Access:	http://link.springer.com/article/10.1186/s12936-020-03319-0

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