High mobility group box 1 contributes to wound healing induced by inhibition of dipeptidylpeptidase 4 in cultured keratinocytes

High mobility group box 1 contributes to wound healing induced by inhibition of dipeptidylpeptidase 4 in cultured keratinocytes

Dipeptidyl peptidase 4 (DPP4) is expressed in various tissues, including the skin, and DPP4 inhibitors, that are currently used for the treatment of diabetes, may be effective also for complications of diabetes that affect the skin. To assess the role of DPP4 in keratinocytes, after creating a scrat...

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Bibliographic Details
Main Authors: Tiziana eSinagra, Sara eMerlo, Simona Federica Spampinato, Rocco eDe Pasquale, Maria Angela eSortino
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-06-01
Series:Frontiers in Pharmacology
Subjects:
Keratinocytes
Skin
diabetes
HMGB1
DPP-4 inhibitors
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00126/full

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