The cost-effectiveness of home phototherapy for hyperbilirubinemia in neonates: results from a randomized controlled trial
Abstract This study aimed to establish the cost-effectiveness of home phototherapy versus hospital phototherapy treating hyperbilirubinemia in neonates more than 36 weeks. Based on clinical results from a randomised controlled trial showing that home phototherapy for hyperbilirubinemia in term neona...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-07-01
|
| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-023-37684-y |
| _version_ | 1797784655150186496 |
|---|---|
| author | Miriam Pettersson Linda Ryen Mats Eriksson Andreas Ohlin |
| author_facet | Miriam Pettersson Linda Ryen Mats Eriksson Andreas Ohlin |
| author_sort | Miriam Pettersson |
| collection | DOAJ |
| description | Abstract This study aimed to establish the cost-effectiveness of home phototherapy versus hospital phototherapy treating hyperbilirubinemia in neonates more than 36 weeks. Based on clinical results from a randomised controlled trial showing that home phototherapy for hyperbilirubinemia in term neonates is as effective as hospital phototherapy, we performed a cost-minimisation analysis to identify the most cost-effective alternative. We included costs for health care resource use as well as costs for transportation in connection with re-visits. The cost per patient was €337 for home phototherapy compared with €1156 for the hospital alternative indicating average cost savings of €819 (95% confidence interval €613–1025) or 71% per patient. Transportation and outpatient costs were higher in the home treatment group and hospital care costs were higher in the hospital group. Sensitivity analysis shows that results are robust also when allowing for uncertainty. Home phototherapy for neonates more than 36 weeks costs less than in-hospital phototherapy while being equally effective, meaning that home phototherapy is a cost-effective alternative to hospital treatment for infants with neonatal hyperbilirubinemia. Trial registration NCT03536078 . Date of registration: 24/05/2018. |
| first_indexed | 2024-03-13T00:42:59Z |
| format | Article |
| id | doaj.art-cd8a55e6b71846ec87afbf49f5ecb620 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-03-13T00:42:59Z |
| publishDate | 2023-07-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-cd8a55e6b71846ec87afbf49f5ecb6202023-07-09T11:13:11ZengNature PortfolioScientific Reports2045-23222023-07-011311710.1038/s41598-023-37684-yThe cost-effectiveness of home phototherapy for hyperbilirubinemia in neonates: results from a randomized controlled trialMiriam Pettersson0Linda Ryen1Mats Eriksson2Andreas Ohlin3Department of Paediatrics, Faculty of Medicine and Health, Örebro UniversityUniversity Health Care Research Center, Faculty of Medicine and Health, Örebro UniversityDepartment of Paediatrics, Faculty of Medicine and Health, Örebro UniversityDepartment of Paediatrics, Faculty of Medicine and Health, Örebro UniversityAbstract This study aimed to establish the cost-effectiveness of home phototherapy versus hospital phototherapy treating hyperbilirubinemia in neonates more than 36 weeks. Based on clinical results from a randomised controlled trial showing that home phototherapy for hyperbilirubinemia in term neonates is as effective as hospital phototherapy, we performed a cost-minimisation analysis to identify the most cost-effective alternative. We included costs for health care resource use as well as costs for transportation in connection with re-visits. The cost per patient was €337 for home phototherapy compared with €1156 for the hospital alternative indicating average cost savings of €819 (95% confidence interval €613–1025) or 71% per patient. Transportation and outpatient costs were higher in the home treatment group and hospital care costs were higher in the hospital group. Sensitivity analysis shows that results are robust also when allowing for uncertainty. Home phototherapy for neonates more than 36 weeks costs less than in-hospital phototherapy while being equally effective, meaning that home phototherapy is a cost-effective alternative to hospital treatment for infants with neonatal hyperbilirubinemia. Trial registration NCT03536078 . Date of registration: 24/05/2018.https://doi.org/10.1038/s41598-023-37684-y |
| spellingShingle | Miriam Pettersson Linda Ryen Mats Eriksson Andreas Ohlin The cost-effectiveness of home phototherapy for hyperbilirubinemia in neonates: results from a randomized controlled trial Scientific Reports |
| title | The cost-effectiveness of home phototherapy for hyperbilirubinemia in neonates: results from a randomized controlled trial |
| title_full | The cost-effectiveness of home phototherapy for hyperbilirubinemia in neonates: results from a randomized controlled trial |
| title_fullStr | The cost-effectiveness of home phototherapy for hyperbilirubinemia in neonates: results from a randomized controlled trial |
| title_full_unstemmed | The cost-effectiveness of home phototherapy for hyperbilirubinemia in neonates: results from a randomized controlled trial |
| title_short | The cost-effectiveness of home phototherapy for hyperbilirubinemia in neonates: results from a randomized controlled trial |
| title_sort | cost effectiveness of home phototherapy for hyperbilirubinemia in neonates results from a randomized controlled trial |
| url | https://doi.org/10.1038/s41598-023-37684-y |
| work_keys_str_mv | AT miriampettersson thecosteffectivenessofhomephototherapyforhyperbilirubinemiainneonatesresultsfromarandomizedcontrolledtrial AT lindaryen thecosteffectivenessofhomephototherapyforhyperbilirubinemiainneonatesresultsfromarandomizedcontrolledtrial AT matseriksson thecosteffectivenessofhomephototherapyforhyperbilirubinemiainneonatesresultsfromarandomizedcontrolledtrial AT andreasohlin thecosteffectivenessofhomephototherapyforhyperbilirubinemiainneonatesresultsfromarandomizedcontrolledtrial AT miriampettersson costeffectivenessofhomephototherapyforhyperbilirubinemiainneonatesresultsfromarandomizedcontrolledtrial AT lindaryen costeffectivenessofhomephototherapyforhyperbilirubinemiainneonatesresultsfromarandomizedcontrolledtrial AT matseriksson costeffectivenessofhomephototherapyforhyperbilirubinemiainneonatesresultsfromarandomizedcontrolledtrial AT andreasohlin costeffectivenessofhomephototherapyforhyperbilirubinemiainneonatesresultsfromarandomizedcontrolledtrial |