TGFβ Signaling in the Pancreatic Tumor Microenvironment

TGFβ Signaling in the Pancreatic Tumor Microenvironment

Pancreatic ductal adenocarcinoma (PDAC) is associated with poor clinical outcomes, largely attributed to incomplete responses to standard therapeutic approaches. Recently, selective inhibitors of the Transforming Growth Factor β (TGFβ) signaling pathway have shown early promise in the treatment of P...

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Bibliographic Details
Main Authors: Daniel R. Principe, Kaytlin E. Timbers, Luke G. Atia, Regina M. Koch, Ajay Rana
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Cancers
Subjects:
pancreatic cancer
TGFβ signaling
tumor microenvironment
Online Access:https://www.mdpi.com/2072-6694/13/20/5086

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