Association of Knee Extensor Muscle Strength and Cardiorespiratory Fitness With Bone Stiffness in Japanese Adults: A Cross-sectional Study
Background: Knee extensor muscle strength and cardiorespiratory fitness (CRF) are major components of physical fitness. Because the interactive association of knee extensor muscle strength and CRF with bone health remains unclear, we aimed to investigate such association in Japanese adults. Methods:...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Japan Epidemiological Association
2022-12-01
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| Series: | Journal of Epidemiology |
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| Online Access: | https://www.jstage.jst.go.jp/article/jea/32/12/32_JE20200581/_pdf |
| _version_ | 1811178022548537344 |
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| author | Takahisa Ohta Junzo Nagashima Wataru Fukuda Hiroyuki Sasai Naokata Ishii |
| author_facet | Takahisa Ohta Junzo Nagashima Wataru Fukuda Hiroyuki Sasai Naokata Ishii |
| author_sort | Takahisa Ohta |
| collection | DOAJ |
| description | Background: Knee extensor muscle strength and cardiorespiratory fitness (CRF) are major components of physical fitness. Because the interactive association of knee extensor muscle strength and CRF with bone health remains unclear, we aimed to investigate such association in Japanese adults. Methods: Altogether, 8,829 Japanese adults (3,731 men and 5,098 women) aged ≥45 years completed the maximum voluntary knee extension test, submaximal exercise test, medical examination, and a questionnaire on lifestyle habits. Using an osteo-sono assessment index, low bone stiffness tendency was defined as 80% under the young-adults mean. Multivariable odds ratios (ORs) and 95% confidence intervals (CIs) were calculated after confounder adjustment. Results: Overall, 542 men (14.5%) and 978 women (19.2%) had low bone stiffness tendency. We observed an inverse association between muscle strength and low bone stiffness tendency after adjustment for CRF in both sexes (P for linear trend <0.001). Compared with the lowest CRF, the multivariable ORs for low bone stiffness tendency in the highest CRF were 0.47 (95% CI, 0.36–0.62) for men and 1.05 (95% CI, 0.82–1.35) for post-menopausal women (P < 0.001 and P = 0.704, respectively). No interactive association between muscle strength and CRF for low bone stiffness tendency existed in both sexes and irrespective of menopausal status. Conclusion: Knee extensor muscle strength and CRF were associated additively, not synergistically, with bone health. Maintaining high levels of both physical fitness components may improve musculoskeletal health in the cohort. The relationship between physical fitness and bone status should be longitudinally investigated in the future. |
| first_indexed | 2024-04-11T06:12:26Z |
| format | Article |
| id | doaj.art-cd9116f58a354d04af3573b4ae94afc4 |
| institution | Directory Open Access Journal |
| issn | 0917-5040 1349-9092 |
| language | English |
| last_indexed | 2024-04-11T06:12:26Z |
| publishDate | 2022-12-01 |
| publisher | Japan Epidemiological Association |
| record_format | Article |
| series | Journal of Epidemiology |
| spelling | doaj.art-cd9116f58a354d04af3573b4ae94afc42022-12-22T04:41:14ZengJapan Epidemiological AssociationJournal of Epidemiology0917-50401349-90922022-12-01321254355010.2188/jea.JE20200581Association of Knee Extensor Muscle Strength and Cardiorespiratory Fitness With Bone Stiffness in Japanese Adults: A Cross-sectional StudyTakahisa Ohta0Junzo Nagashima1Wataru Fukuda2Hiroyuki Sasai3Naokata Ishii4Graduate School of Health and Sport Science, Nippon Sport Science University, Tokyo, JapanYokohama Sports Medical Center, Nissan Stadium, Kanagawa, JapanGraduate School of Health and Sport Science, Nippon Sport Science University, Tokyo, JapanResearch Team for Promoting Independence and Mental Health, Tokyo Metropolitan Institute of Gerontology, Tokyo, JapanDepartment of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo, Tokyo, JapanBackground: Knee extensor muscle strength and cardiorespiratory fitness (CRF) are major components of physical fitness. Because the interactive association of knee extensor muscle strength and CRF with bone health remains unclear, we aimed to investigate such association in Japanese adults. Methods: Altogether, 8,829 Japanese adults (3,731 men and 5,098 women) aged ≥45 years completed the maximum voluntary knee extension test, submaximal exercise test, medical examination, and a questionnaire on lifestyle habits. Using an osteo-sono assessment index, low bone stiffness tendency was defined as 80% under the young-adults mean. Multivariable odds ratios (ORs) and 95% confidence intervals (CIs) were calculated after confounder adjustment. Results: Overall, 542 men (14.5%) and 978 women (19.2%) had low bone stiffness tendency. We observed an inverse association between muscle strength and low bone stiffness tendency after adjustment for CRF in both sexes (P for linear trend <0.001). Compared with the lowest CRF, the multivariable ORs for low bone stiffness tendency in the highest CRF were 0.47 (95% CI, 0.36–0.62) for men and 1.05 (95% CI, 0.82–1.35) for post-menopausal women (P < 0.001 and P = 0.704, respectively). No interactive association between muscle strength and CRF for low bone stiffness tendency existed in both sexes and irrespective of menopausal status. Conclusion: Knee extensor muscle strength and CRF were associated additively, not synergistically, with bone health. Maintaining high levels of both physical fitness components may improve musculoskeletal health in the cohort. The relationship between physical fitness and bone status should be longitudinally investigated in the future.https://www.jstage.jst.go.jp/article/jea/32/12/32_JE20200581/_pdfknee extensor muscle strengthcardiorespiratory fitnessbone stiffnessquantitative ultrasound |
| spellingShingle | Takahisa Ohta Junzo Nagashima Wataru Fukuda Hiroyuki Sasai Naokata Ishii Association of Knee Extensor Muscle Strength and Cardiorespiratory Fitness With Bone Stiffness in Japanese Adults: A Cross-sectional Study Journal of Epidemiology knee extensor muscle strength cardiorespiratory fitness bone stiffness quantitative ultrasound |
| title | Association of Knee Extensor Muscle Strength and Cardiorespiratory Fitness With Bone Stiffness in Japanese Adults: A Cross-sectional Study |
| title_full | Association of Knee Extensor Muscle Strength and Cardiorespiratory Fitness With Bone Stiffness in Japanese Adults: A Cross-sectional Study |
| title_fullStr | Association of Knee Extensor Muscle Strength and Cardiorespiratory Fitness With Bone Stiffness in Japanese Adults: A Cross-sectional Study |
| title_full_unstemmed | Association of Knee Extensor Muscle Strength and Cardiorespiratory Fitness With Bone Stiffness in Japanese Adults: A Cross-sectional Study |
| title_short | Association of Knee Extensor Muscle Strength and Cardiorespiratory Fitness With Bone Stiffness in Japanese Adults: A Cross-sectional Study |
| title_sort | association of knee extensor muscle strength and cardiorespiratory fitness with bone stiffness in japanese adults a cross sectional study |
| topic | knee extensor muscle strength cardiorespiratory fitness bone stiffness quantitative ultrasound |
| url | https://www.jstage.jst.go.jp/article/jea/32/12/32_JE20200581/_pdf |
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