Design, Synthesis, and Biological Evaluation of Novel Thienopyrimidine Derivatives as PI3Kα Inhibitors

Design, Synthesis, and Biological Evaluation of Novel Thienopyrimidine Derivatives as PI3Kα Inhibitors

Three series of novel thienopyrimidine derivatives <b>9a</b>−<b>l</b>, <b>15a</b>−<b>l</b>, and <b>18a</b>−<b>h</b> were designed and synthesized, and their IC<sub>50</sub> values agains...

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Bibliographic Details
Main Authors:	Lide Yu, Qinqin Wang, Caolin Wang, Binliang Zhang, Zunhua Yang, Yuanying Fang, Wufu Zhu, Pengwu Zheng
Format:	Article
Language:	English
Published:	MDPI AG 2019-09-01
Series:	Molecules
Subjects:	Thienopyrimidine Pyrazole PI3Kα inhibitor
Online Access:	https://www.mdpi.com/1420-3049/24/19/3422

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