Susceptibility Pattern of Neisseria gonorrhoeae towards Cefixime and Ceftriaxone using Kirby-Bauer Method in Dr. Saiful Anwar General Hospital Malang
Background: Gonorrhea remains the second most common sexually transmitted infection (STI) in the world with an increasing number of cases. Oral cefixime and IM ceftriaxone are still the mainstay therapy for gonorrhea in Indonesia. However, previous studies suggested possible resistance to ceftriaxon...
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| Format: | Article |
| Language: | Indonesian |
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Department of Dermatology and Venereology, Faculty of Medicine, Universitas Airlangga
2020-07-01
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| Series: | Berkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology) |
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| Online Access: | https://e-journal.unair.ac.id/BIKK/article/view/14429 |
| _version_ | 1797506057006743552 |
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| author | Lita Setyowatie Tantari SHW Inneke Yulian |
| author_facet | Lita Setyowatie Tantari SHW Inneke Yulian |
| author_sort | Lita Setyowatie |
| collection | DOAJ |
| description | Background: Gonorrhea remains the second most common sexually transmitted infection (STI) in the world with an increasing number of cases. Oral cefixime and IM ceftriaxone are still the mainstay therapy for gonorrhea in Indonesia. However, previous studies suggested possible resistance to ceftriaxone and cefixime, which are the first-line treatment of gonorrhea. To date, there are no data available regarding the susceptibility of these antibiotics for the treatment of gonorrhea in Dr. Saiful Anwar General Hospital (RSSA) Malang. Purpose: Determine susceptibility pattern of Neisseria gonorrhoeaetowards cefixime and ceftriaxone in RSSA Malang. Methods: The samples were patients of the Outpatient Clinic of Dermatology and Venereology Department with a symptom of discharge which contained Gram-negative diplococcus after Gram staining and had a positive culture of Neisseria gonorrhoeae. Susceptibility testing for cefixime and ceftriaxone antibiotics were performed using the Kirby-Bauer method. The data are presented in percentages. Result: Antibiotic susceptibility test results showed that 80.77% of Neisseria gonorrhoeaeisolates were still susceptible to cefixime, and 80.77% of isolates were still susceptible to ceftriaxone. Conclusion: Cefixime and ceftriaxone are still effective as gonorrhea therapy in RSSA Malang. |
| first_indexed | 2024-03-10T04:27:09Z |
| format | Article |
| id | doaj.art-cda33bfdf0164cdfae66dd121a4446c7 |
| institution | Directory Open Access Journal |
| issn | 1978-4279 2549-4082 |
| language | Indonesian |
| last_indexed | 2024-03-10T04:27:09Z |
| publishDate | 2020-07-01 |
| publisher | Department of Dermatology and Venereology, Faculty of Medicine, Universitas Airlangga |
| record_format | Article |
| series | Berkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology) |
| spelling | doaj.art-cda33bfdf0164cdfae66dd121a4446c72023-11-23T06:33:04ZindDepartment of Dermatology and Venereology, Faculty of Medicine, Universitas AirlanggaBerkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology)1978-42792549-40822020-07-0132210311010.20473/bikk.V32.2.2020.103-11011715Susceptibility Pattern of Neisseria gonorrhoeae towards Cefixime and Ceftriaxone using Kirby-Bauer Method in Dr. Saiful Anwar General Hospital MalangLita Setyowatie0Tantari SHW1Inneke Yulian2Department Dermatology and Venereology, Faculty of Medicine, University of Brawijaya /Dr. Saiful Anwar General Hospital, MalangDepartment Dermatology and Venereology, Faculty of Medicine, University of Brawijaya /Dr. Saiful Anwar General Hospital, MalangDepartment Dermatology and Venereology, Faculty of Medicine, University of Brawijaya /Dr. Saiful Anwar General Hospital, MalangBackground: Gonorrhea remains the second most common sexually transmitted infection (STI) in the world with an increasing number of cases. Oral cefixime and IM ceftriaxone are still the mainstay therapy for gonorrhea in Indonesia. However, previous studies suggested possible resistance to ceftriaxone and cefixime, which are the first-line treatment of gonorrhea. To date, there are no data available regarding the susceptibility of these antibiotics for the treatment of gonorrhea in Dr. Saiful Anwar General Hospital (RSSA) Malang. Purpose: Determine susceptibility pattern of Neisseria gonorrhoeaetowards cefixime and ceftriaxone in RSSA Malang. Methods: The samples were patients of the Outpatient Clinic of Dermatology and Venereology Department with a symptom of discharge which contained Gram-negative diplococcus after Gram staining and had a positive culture of Neisseria gonorrhoeae. Susceptibility testing for cefixime and ceftriaxone antibiotics were performed using the Kirby-Bauer method. The data are presented in percentages. Result: Antibiotic susceptibility test results showed that 80.77% of Neisseria gonorrhoeaeisolates were still susceptible to cefixime, and 80.77% of isolates were still susceptible to ceftriaxone. Conclusion: Cefixime and ceftriaxone are still effective as gonorrhea therapy in RSSA Malang.https://e-journal.unair.ac.id/BIKK/article/view/14429susceptibilityresistancecefiximeceftriaxone |
| spellingShingle | Lita Setyowatie Tantari SHW Inneke Yulian Susceptibility Pattern of Neisseria gonorrhoeae towards Cefixime and Ceftriaxone using Kirby-Bauer Method in Dr. Saiful Anwar General Hospital Malang Berkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology) susceptibility resistance cefixime ceftriaxone |
| title | Susceptibility Pattern of Neisseria gonorrhoeae towards Cefixime and Ceftriaxone using Kirby-Bauer Method in Dr. Saiful Anwar General Hospital Malang |
| title_full | Susceptibility Pattern of Neisseria gonorrhoeae towards Cefixime and Ceftriaxone using Kirby-Bauer Method in Dr. Saiful Anwar General Hospital Malang |
| title_fullStr | Susceptibility Pattern of Neisseria gonorrhoeae towards Cefixime and Ceftriaxone using Kirby-Bauer Method in Dr. Saiful Anwar General Hospital Malang |
| title_full_unstemmed | Susceptibility Pattern of Neisseria gonorrhoeae towards Cefixime and Ceftriaxone using Kirby-Bauer Method in Dr. Saiful Anwar General Hospital Malang |
| title_short | Susceptibility Pattern of Neisseria gonorrhoeae towards Cefixime and Ceftriaxone using Kirby-Bauer Method in Dr. Saiful Anwar General Hospital Malang |
| title_sort | susceptibility pattern of neisseria gonorrhoeae towards cefixime and ceftriaxone using kirby bauer method in dr saiful anwar general hospital malang |
| topic | susceptibility resistance cefixime ceftriaxone |
| url | https://e-journal.unair.ac.id/BIKK/article/view/14429 |
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