Resveratrol and Its Analogs: Potent Agents to Reverse Epithelial-to-Mesenchymal Transition in Tumors

Resveratrol and Its Analogs: Potent Agents to Reverse Epithelial-to-Mesenchymal Transition in Tumors

Epithelial-to-mesenchymal transition (EMT), a complicated program through which polarized epithelial cells acquire motile mesothelial traits, is regulated by tumor microenvironment. EMT is involved in tumor progression, invasion and metastasis via reconstructing the cytoskeleton and degrading the tu...

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Bibliographic Details
Main Authors: Kaibo Guo, Yuqian Feng, Xueer Zheng, Leitao Sun, Harpreet S. Wasan, Shanming Ruan, Minhe Shen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Oncology
Subjects:
epithelial-to-mesenchymal transition
metastasis
chemoresistance
cancer cell stemness
resveratrol
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.644134/full

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