Is there Emergence of Clinical HBV Resistance Under Long-Term HBV Combination Therapy? A Challenging Case Report
A first case of clinical tenofovir (TDF) HBV resistance in an HIV/HBV coinfected patient who developed an acute flare of hepatitis B is reported. The clinical course was accompanied by signs of acute liver failure after being on successful HBV treatment with tenofovir and persistently undetectable H...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2010-07-01
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| Series: | Viruses |
| Subjects: | |
| Online Access: | http://www.mdpi.com/1999-4915/2/8/1564/ |
| _version_ | 1818157394835800064 |
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| author | Jürgen Kurt Rockstroh Jan van Lunzen Stefan Schmiedel Hüseyin Sirma Christian Noah Knud Schewe Oliver Schildgen |
| author_facet | Jürgen Kurt Rockstroh Jan van Lunzen Stefan Schmiedel Hüseyin Sirma Christian Noah Knud Schewe Oliver Schildgen |
| author_sort | Jürgen Kurt Rockstroh |
| collection | DOAJ |
| description | A first case of clinical tenofovir (TDF) HBV resistance in an HIV/HBV coinfected patient who developed an acute flare of hepatitis B is reported. The clinical course was accompanied by signs of acute liver failure after being on successful HBV treatment with tenofovir and persistently undetectable HBV-DNA viral load for over five years. |
| first_indexed | 2024-12-11T15:13:30Z |
| format | Article |
| id | doaj.art-cdabd5aea8584a96b1d8f27b6b00c569 |
| institution | Directory Open Access Journal |
| issn | 1999-4915 |
| language | English |
| last_indexed | 2024-12-11T15:13:30Z |
| publishDate | 2010-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Viruses |
| spelling | doaj.art-cdabd5aea8584a96b1d8f27b6b00c5692022-12-22T01:00:41ZengMDPI AGViruses1999-49152010-07-01281564157010.3390/v2081564Is there Emergence of Clinical HBV Resistance Under Long-Term HBV Combination Therapy? A Challenging Case ReportJürgen Kurt RockstrohJan van LunzenStefan SchmiedelHüseyin SirmaChristian NoahKnud ScheweOliver SchildgenA first case of clinical tenofovir (TDF) HBV resistance in an HIV/HBV coinfected patient who developed an acute flare of hepatitis B is reported. The clinical course was accompanied by signs of acute liver failure after being on successful HBV treatment with tenofovir and persistently undetectable HBV-DNA viral load for over five years.http://www.mdpi.com/1999-4915/2/8/1564/HIV-HBV-coinfectiontenofovirclinical HBV resistance |
| spellingShingle | Jürgen Kurt Rockstroh Jan van Lunzen Stefan Schmiedel Hüseyin Sirma Christian Noah Knud Schewe Oliver Schildgen Is there Emergence of Clinical HBV Resistance Under Long-Term HBV Combination Therapy? A Challenging Case Report Viruses HIV-HBV-coinfection tenofovir clinical HBV resistance |
| title | Is there Emergence of Clinical HBV Resistance Under Long-Term HBV Combination Therapy? A Challenging Case Report |
| title_full | Is there Emergence of Clinical HBV Resistance Under Long-Term HBV Combination Therapy? A Challenging Case Report |
| title_fullStr | Is there Emergence of Clinical HBV Resistance Under Long-Term HBV Combination Therapy? A Challenging Case Report |
| title_full_unstemmed | Is there Emergence of Clinical HBV Resistance Under Long-Term HBV Combination Therapy? A Challenging Case Report |
| title_short | Is there Emergence of Clinical HBV Resistance Under Long-Term HBV Combination Therapy? A Challenging Case Report |
| title_sort | is there emergence of clinical hbv resistance under long term hbv combination therapy a challenging case report |
| topic | HIV-HBV-coinfection tenofovir clinical HBV resistance |
| url | http://www.mdpi.com/1999-4915/2/8/1564/ |
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