The protective effect and mechanism of catalpol on high glucose-induced podocyte injury

The protective effect and mechanism of catalpol on high glucose-induced podocyte injury

Abstract Background Catalpol, a natural iridoid glycoside in Rehmannia glutinosa, can alleviate proteinuria associated with diabetic nephropathy (DN), however, whether catalpol has a protective effect against podocyte injury in DN remains unclear. Methods In this study, we used a high glucose (HG)-i...

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Bibliographic Details
Main Authors: Yan Chen, Qingpu Liu, Zengfu Shan, Yingying Zhao, Meng Li, Baiyan Wang, Xiaoke Zheng, Weisheng Feng
Format: Article
Language:English
Published: BMC 2019-09-01
Series:BMC Complementary and Alternative Medicine
Subjects:
Rehmannia glutinosa
Catalpol
Podocyte injury
Diabetic nephropathy
Mechanism
Online Access:http://link.springer.com/article/10.1186/s12906-019-2656-8

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