Artificial Intelligence Assisted Pharmacophore Design for Philadelphia Chromosome-Positive Leukemia with Gamma-Tocotrienol: A Toxicity Comparison Approach with Asciminib

Artificial Intelligence Assisted Pharmacophore Design for Philadelphia Chromosome-Positive Leukemia with Gamma-Tocotrienol: A Toxicity Comparison Approach with Asciminib

BCR-ABL1 is a fusion protein as a result of a unique chromosomal translocation (producing the so-called Philadelphia chromosome) that serves as a clinical biomarker primarily for chronic myeloid leukemia (CML); the Philadelphia chromosome also occurs, albeit rather rarely, in other types of leukemia...

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Bibliographic Details
Main Authors:	Muhammad Naveed, Noor ul Ain, Tariq Aziz, Khushbakht Javed, Muhammad Aqib Shabbir, Metab Alharbi, Abdulrahman Alsahammari, Abdullah F. Alasmari
Format:	Article
Language:	English
Published:	MDPI AG 2023-03-01
Series:	Biomedicines
Subjects:	Philadelphia chromosome-positive leukemia chronic myeloid leukemia artificial intelligence gamma-tocotrienol toxicity asciminib
Online Access:	https://www.mdpi.com/2227-9059/11/4/1041

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