Analysis of BRCT5 domain-containing proteins reveals a new component of DNA damage repair in Arabidopsis
The integrity of plant genetic information is constantly challenged by various internal and external factors. Therefore, plants use a sophisticated molecular network to identify, signal and repair damaged DNA. Here, we report on the identification and analysis of four uncharacterized Arabidopsis BRC...
Main Authors: | Jovanka Vladejić, Fen Yang, Eva Dvořák Tomaštíková, Jaroslav Doležel, Jan J. Palecek, Ales Pecinka |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-12-01
|
Series: | Frontiers in Plant Science |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fpls.2022.1023358/full |
Similar Items
-
BRCA1 and Its Vulnerable C-Terminal BRCT Domain: Structure, Function, Genetic Mutations and Links to Diagnosis and Treatment of Breast and Ovarian Cancer
by: Tala Ismail, et al.
Published: (2024-03-01) -
BRCT Domains: Structure, Functions, and Implications in Disease—New Therapeutic Targets for Innovative Drug Discovery against Infections
by: José Peña-Guerrero, et al.
Published: (2023-06-01) -
The BRCT Domain from the Homologue of the Oncogene PES1 in <i>Leishmania major</i> (LmjPES) Promotes Malignancy and Drug Resistance in Mammalian Cells
by: Esther Larrea, et al.
Published: (2022-10-01) -
Discovery and Validation of Lmj_04_BRCT Domain, a Novel Therapeutic Target: Identification of Candidate Drugs for Leishmaniasis
by: José Peña-Guerrero, et al.
Published: (2021-09-01) -
Trans-activation-based risk assessment of BRCA1 BRCT variants with unknown clinical significance
by: Jonas Langerud, et al.
Published: (2018-11-01)