Genetic effects of sterol regulatory element binding proteins and fatty acid-binding protein4 on the fatty acid composition of Korean cattle (Hanwoo)
Objective This study identifies single-nucleotide polymorphisms (SNP) or gene combinations that affect the flavor and quality of Korean cattle (Hanwoo) by using the SNP Harvester method. Methods Four economic traits (oleic acid [C18:1], saturated fatty acids), monounsaturated fatty acids, and marbli...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Asian-Australasian Association of Animal Production Societies
2017-02-01
|
| Series: | Asian-Australasian Journal of Animal Sciences |
| Subjects: | |
| Online Access: | http://www.ajas.info/upload/pdf/ajas-30-2-160.pdf |
| _version_ | 1811283026194202624 |
|---|---|
| author | Dong-Yep Oh Jea-Young Lee Ji-Eun Jang Seung-Uk Lee |
| author_facet | Dong-Yep Oh Jea-Young Lee Ji-Eun Jang Seung-Uk Lee |
| author_sort | Dong-Yep Oh |
| collection | DOAJ |
| description | Objective This study identifies single-nucleotide polymorphisms (SNP) or gene combinations that affect the flavor and quality of Korean cattle (Hanwoo) by using the SNP Harvester method. Methods Four economic traits (oleic acid [C18:1], saturated fatty acids), monounsaturated fatty acids, and marbling score) were adjusted for environmental factors in order to focus solely on genetic effects. The SNP Harvester method was used to investigate gene combinations (two-way gene interactions) associated with these economic traits. Further, a multifactor dimensionality reduction method was used to identify superior genotypes in gene combinations. Results Table 3 to 4 show the analysis results for differences between superior genotypes and others for selected major gene combinations using the multifactor dimensionality reduction method. Environmental factors were adjusted for in order to evaluate only the genetic effect. Table 5 shows the adjustment effect by comparing the accuracy before and after correction in two-way gene interactions. Conclusion The g.3977-325 T>C and (g.2988 A>G, g.3977-325 T>C) combinations of fatty acid-binding protein4 were the superior gene, and the superior genotype combinations across all economic traits were the CC genotype at g.3977-325 T>C and the AACC, GACC, GGCC genotypes of (g.2988 A>G, g.3977-325 T>C). |
| first_indexed | 2024-04-13T02:03:11Z |
| format | Article |
| id | doaj.art-cdb4d050fa7c428cade934409786bd35 |
| institution | Directory Open Access Journal |
| issn | 1011-2367 1976-5517 |
| language | English |
| last_indexed | 2024-04-13T02:03:11Z |
| publishDate | 2017-02-01 |
| publisher | Asian-Australasian Association of Animal Production Societies |
| record_format | Article |
| series | Asian-Australasian Journal of Animal Sciences |
| spelling | doaj.art-cdb4d050fa7c428cade934409786bd352022-12-22T03:07:33ZengAsian-Australasian Association of Animal Production SocietiesAsian-Australasian Journal of Animal Sciences1011-23671976-55172017-02-0130216016610.5713/ajas.16.026223605Genetic effects of sterol regulatory element binding proteins and fatty acid-binding protein4 on the fatty acid composition of Korean cattle (Hanwoo)Dong-Yep Oh0Jea-Young Lee1Ji-Eun Jang2Seung-Uk Lee3 Livestock Research institute, Yeongju 750-871, Korea Department of Statistics, Yeungnam University, Gyeongsan 712-749, Korea Department of Statistics, Yeungnam University, Gyeongsan 712-749, Korea Department of Civil and Environmental Engineering, National University of Singapore, Singapore 117576, SingaporeObjective This study identifies single-nucleotide polymorphisms (SNP) or gene combinations that affect the flavor and quality of Korean cattle (Hanwoo) by using the SNP Harvester method. Methods Four economic traits (oleic acid [C18:1], saturated fatty acids), monounsaturated fatty acids, and marbling score) were adjusted for environmental factors in order to focus solely on genetic effects. The SNP Harvester method was used to investigate gene combinations (two-way gene interactions) associated with these economic traits. Further, a multifactor dimensionality reduction method was used to identify superior genotypes in gene combinations. Results Table 3 to 4 show the analysis results for differences between superior genotypes and others for selected major gene combinations using the multifactor dimensionality reduction method. Environmental factors were adjusted for in order to evaluate only the genetic effect. Table 5 shows the adjustment effect by comparing the accuracy before and after correction in two-way gene interactions. Conclusion The g.3977-325 T>C and (g.2988 A>G, g.3977-325 T>C) combinations of fatty acid-binding protein4 were the superior gene, and the superior genotype combinations across all economic traits were the CC genotype at g.3977-325 T>C and the AACC, GACC, GGCC genotypes of (g.2988 A>G, g.3977-325 T>C).http://www.ajas.info/upload/pdf/ajas-30-2-160.pdfFatty Acid-binding Protein4 ()Single-Nucleotide Polymorphism (SNP)SNP HarvesterSterol Regulatory Element Binding Proteins ()Hanwoo |
| spellingShingle | Dong-Yep Oh Jea-Young Lee Ji-Eun Jang Seung-Uk Lee Genetic effects of sterol regulatory element binding proteins and fatty acid-binding protein4 on the fatty acid composition of Korean cattle (Hanwoo) Asian-Australasian Journal of Animal Sciences Fatty Acid-binding Protein4 () Single-Nucleotide Polymorphism (SNP) SNP Harvester Sterol Regulatory Element Binding Proteins () Hanwoo |
| title | Genetic effects of sterol regulatory element binding proteins and fatty acid-binding protein4 on the fatty acid composition of Korean cattle (Hanwoo) |
| title_full | Genetic effects of sterol regulatory element binding proteins and fatty acid-binding protein4 on the fatty acid composition of Korean cattle (Hanwoo) |
| title_fullStr | Genetic effects of sterol regulatory element binding proteins and fatty acid-binding protein4 on the fatty acid composition of Korean cattle (Hanwoo) |
| title_full_unstemmed | Genetic effects of sterol regulatory element binding proteins and fatty acid-binding protein4 on the fatty acid composition of Korean cattle (Hanwoo) |
| title_short | Genetic effects of sterol regulatory element binding proteins and fatty acid-binding protein4 on the fatty acid composition of Korean cattle (Hanwoo) |
| title_sort | genetic effects of sterol regulatory element binding proteins and fatty acid binding protein4 on the fatty acid composition of korean cattle hanwoo |
| topic | Fatty Acid-binding Protein4 () Single-Nucleotide Polymorphism (SNP) SNP Harvester Sterol Regulatory Element Binding Proteins () Hanwoo |
| url | http://www.ajas.info/upload/pdf/ajas-30-2-160.pdf |
| work_keys_str_mv | AT dongyepoh geneticeffectsofsterolregulatoryelementbindingproteinsandfattyacidbindingprotein4onthefattyacidcompositionofkoreancattlehanwoo AT jeayounglee geneticeffectsofsterolregulatoryelementbindingproteinsandfattyacidbindingprotein4onthefattyacidcompositionofkoreancattlehanwoo AT jieunjang geneticeffectsofsterolregulatoryelementbindingproteinsandfattyacidbindingprotein4onthefattyacidcompositionofkoreancattlehanwoo AT seunguklee geneticeffectsofsterolregulatoryelementbindingproteinsandfattyacidbindingprotein4onthefattyacidcompositionofkoreancattlehanwoo |