Blood-Based Detection of BRAF V600E in Gliomas and Brain Tumor Metastasis

Liquid biopsy provides a minimally invasive platform for the detection of tumor-derived information, including hotspot mutations, such as BRAF V600E. In this study, we provide evidence of the technical development of a ddPCR assay for the detection of BRAF V600E mutations in the plasma of patients w...

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Bibliographic Details
Main Authors: Keiko M. Kang, Koushik Muralidharan, Anudeep Yekula, Julia L. Small, Zachary S. Rosh, Pamela S. Jones, Bob S. Carter, Leonora Balaj
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/13/6/1227