Pharmacological Treatment of Type-2-Diabetes and Cardiovascular Comorbidities: Differences between Undocumented Migrants and Natives in Italy
Diabetes prevalence is growing worldwide, especially in some populations. Though migrations seem to contribute to the presence in host countries of a significant number of patients with diabetes and its comorbidities, very little is known about the health conditions of undocumented migrants. We retr...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-12-01
|
| Series: | Healthcare |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2227-9032/11/1/4 |
| _version_ | 1797625782229532672 |
|---|---|
| author | Gianfrancesco Fiorini Giacomo Pellegrini Matteo Franchi Angela Ida Pincelli Antonello Emilio Rigamonti Giovanni Corrao Alessandro Sartorio Silvano Gabriele Cella |
| author_facet | Gianfrancesco Fiorini Giacomo Pellegrini Matteo Franchi Angela Ida Pincelli Antonello Emilio Rigamonti Giovanni Corrao Alessandro Sartorio Silvano Gabriele Cella |
| author_sort | Gianfrancesco Fiorini |
| collection | DOAJ |
| description | Diabetes prevalence is growing worldwide, especially in some populations. Though migrations seem to contribute to the presence in host countries of a significant number of patients with diabetes and its comorbidities, very little is known about the health conditions of undocumented migrants. We retrospectively studied 838 patients with type 2 diabetes mellitus (T2DM), 425 Italians followed by the diabetes clinic of a university hospital, and 413 undocumented migrants receiving assistance from a non-governmental organization. We analyzed their demographic and clinical data together with the medications they were on. The prevalence of the use of specific classes of drugs was compared between undocumented migrants and Italians by fitting a Poisson regression model, and the results were reported as prevalence rate ratios (PRRs) with a 95% confidence interval. Undocumented migrants with T2DM received fewer medications for cardiovascular (CV) conditions (PRR: 0.68, 0.60 to 0.76) than Italians, after correcting for confounding factors. Only sulfonylureas were more frequently used in undocumented migrants. The causes of these differences are not completely clear, but social, cultural, and economic factors can have an important role. More efforts are needed to provide appropriate treatment of diabetes and its CV comorbidities to undocumented migrants. |
| first_indexed | 2024-03-11T10:01:19Z |
| format | Article |
| id | doaj.art-cdb9a25a63054172a78d609874f4bf3f |
| institution | Directory Open Access Journal |
| issn | 2227-9032 |
| language | English |
| last_indexed | 2024-03-11T10:01:19Z |
| publishDate | 2022-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Healthcare |
| spelling | doaj.art-cdb9a25a63054172a78d609874f4bf3f2023-11-16T15:24:11ZengMDPI AGHealthcare2227-90322022-12-01111410.3390/healthcare11010004Pharmacological Treatment of Type-2-Diabetes and Cardiovascular Comorbidities: Differences between Undocumented Migrants and Natives in ItalyGianfrancesco Fiorini0Giacomo Pellegrini1Matteo Franchi2Angela Ida Pincelli3Antonello Emilio Rigamonti4Giovanni Corrao5Alessandro Sartorio6Silvano Gabriele Cella7Istituti Clinici Zucchi, Gruppo San Donato, 20900 Monza, ItalyNational Centre for Healthcare Research and Pharmacoepidemiology, 20126 Milan, ItalyNational Centre for Healthcare Research and Pharmacoepidemiology, 20126 Milan, ItalyEndocrinology and Diabetes Center, San Gerardo Hospital, 20900 Monza, ItalyLaboratory of Clinical Pharmacology and Pharmacoepidemiology, Department of Clinical Sciences and Community Health, University of Milan, 20122 Milan, ItalyNational Centre for Healthcare Research and Pharmacoepidemiology, 20126 Milan, ItalyIstituto Auxologico Italiano, IRCCS, Experimental Laboratory for Auxo-Endocrinological Research, 28824 Piancavallo-Verbania, ItalyNational Centre for Healthcare Research and Pharmacoepidemiology, 20126 Milan, ItalyDiabetes prevalence is growing worldwide, especially in some populations. Though migrations seem to contribute to the presence in host countries of a significant number of patients with diabetes and its comorbidities, very little is known about the health conditions of undocumented migrants. We retrospectively studied 838 patients with type 2 diabetes mellitus (T2DM), 425 Italians followed by the diabetes clinic of a university hospital, and 413 undocumented migrants receiving assistance from a non-governmental organization. We analyzed their demographic and clinical data together with the medications they were on. The prevalence of the use of specific classes of drugs was compared between undocumented migrants and Italians by fitting a Poisson regression model, and the results were reported as prevalence rate ratios (PRRs) with a 95% confidence interval. Undocumented migrants with T2DM received fewer medications for cardiovascular (CV) conditions (PRR: 0.68, 0.60 to 0.76) than Italians, after correcting for confounding factors. Only sulfonylureas were more frequently used in undocumented migrants. The causes of these differences are not completely clear, but social, cultural, and economic factors can have an important role. More efforts are needed to provide appropriate treatment of diabetes and its CV comorbidities to undocumented migrants.https://www.mdpi.com/2227-9032/11/1/4diabetesundocumented migrantscardiovascular diseasesantidiabetic agents |
| spellingShingle | Gianfrancesco Fiorini Giacomo Pellegrini Matteo Franchi Angela Ida Pincelli Antonello Emilio Rigamonti Giovanni Corrao Alessandro Sartorio Silvano Gabriele Cella Pharmacological Treatment of Type-2-Diabetes and Cardiovascular Comorbidities: Differences between Undocumented Migrants and Natives in Italy Healthcare diabetes undocumented migrants cardiovascular diseases antidiabetic agents |
| title | Pharmacological Treatment of Type-2-Diabetes and Cardiovascular Comorbidities: Differences between Undocumented Migrants and Natives in Italy |
| title_full | Pharmacological Treatment of Type-2-Diabetes and Cardiovascular Comorbidities: Differences between Undocumented Migrants and Natives in Italy |
| title_fullStr | Pharmacological Treatment of Type-2-Diabetes and Cardiovascular Comorbidities: Differences between Undocumented Migrants and Natives in Italy |
| title_full_unstemmed | Pharmacological Treatment of Type-2-Diabetes and Cardiovascular Comorbidities: Differences between Undocumented Migrants and Natives in Italy |
| title_short | Pharmacological Treatment of Type-2-Diabetes and Cardiovascular Comorbidities: Differences between Undocumented Migrants and Natives in Italy |
| title_sort | pharmacological treatment of type 2 diabetes and cardiovascular comorbidities differences between undocumented migrants and natives in italy |
| topic | diabetes undocumented migrants cardiovascular diseases antidiabetic agents |
| url | https://www.mdpi.com/2227-9032/11/1/4 |
| work_keys_str_mv | AT gianfrancescofiorini pharmacologicaltreatmentoftype2diabetesandcardiovascularcomorbiditiesdifferencesbetweenundocumentedmigrantsandnativesinitaly AT giacomopellegrini pharmacologicaltreatmentoftype2diabetesandcardiovascularcomorbiditiesdifferencesbetweenundocumentedmigrantsandnativesinitaly AT matteofranchi pharmacologicaltreatmentoftype2diabetesandcardiovascularcomorbiditiesdifferencesbetweenundocumentedmigrantsandnativesinitaly AT angelaidapincelli pharmacologicaltreatmentoftype2diabetesandcardiovascularcomorbiditiesdifferencesbetweenundocumentedmigrantsandnativesinitaly AT antonelloemiliorigamonti pharmacologicaltreatmentoftype2diabetesandcardiovascularcomorbiditiesdifferencesbetweenundocumentedmigrantsandnativesinitaly AT giovannicorrao pharmacologicaltreatmentoftype2diabetesandcardiovascularcomorbiditiesdifferencesbetweenundocumentedmigrantsandnativesinitaly AT alessandrosartorio pharmacologicaltreatmentoftype2diabetesandcardiovascularcomorbiditiesdifferencesbetweenundocumentedmigrantsandnativesinitaly AT silvanogabrielecella pharmacologicaltreatmentoftype2diabetesandcardiovascularcomorbiditiesdifferencesbetweenundocumentedmigrantsandnativesinitaly |