Gamma-Tocotrienol Protects the Intestine from Radiation Potentially by Accelerating Mesenchymal Immune Cell Recovery
Natural antioxidant gamma-tocotrienol (GT3), a vitamin E family member, provides intestinal radiation protection. We seek to understand whether this protection is mediated via mucosal epithelial stem cells or sub-mucosal mesenchymal immune cells. Vehicle- or GT3-treated male CD2F1 mice were exposed...
Main Authors: | Sarita Garg, Ratan Sadhukhan, Sudip Banerjee, Alena V. Savenka, Alexei G. Basnakian, Victoria McHargue, Junru Wang, Snehalata A. Pawar, Sanchita P. Ghosh, Jerry Ware, Martin Hauer-Jensen, Rupak Pathak |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-03-01
|
Series: | Antioxidants |
Subjects: | |
Online Access: | http://www.mdpi.com/2076-3921/8/3/57 |
Similar Items
-
Cebpd Is Essential for Gamma-Tocotrienol Mediated Protection against Radiation-Induced Hematopoietic and Intestinal Injury
by: Sudip Banerjee, et al.
Published: (2018-04-01) -
Effects of Gamma-Tocotrienol on Partial-Body Irradiation-Induced Intestinal Injury in a Nonhuman Primate Model
by: Sarita Garg, et al.
Published: (2022-09-01) -
Effects of Gamma-Tocotrienol on Intestinal Injury in a GI-Specific Acute Radiation Syndrome Model in Nonhuman Primate
by: Sarita Garg, et al.
Published: (2022-04-01) -
The Vitamin E Analog Gamma-Tocotrienol (GT3) and Statins Synergistically Up-Regulate Endothelial Thrombomodulin (TM)
by: Rupak Pathak, et al.
Published: (2016-11-01) -
Thrombomodulin contributes to gamma tocotrienol-mediated lethality protection and hematopoietic cell recovery in irradiated mice.
by: Rupak Pathak, et al.
Published: (2015-01-01)