18FDG-microPET and MR DTI findings in Tor1a+/− heterozygous knock-out mice
TorsinA is an important protein in brain development, and plays a role in the regulation of neurite outgrowth and synaptic function. Patients with the most common form of genetic dystonia carry a mutation (DYT1) in one copy of the Tor1a gene, a 3-bp deletion, causing removal of a single glutamic aci...
| Автори: | , , , , |
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| Формат: | Стаття |
| Мова: | English |
| Опубліковано: |
Elsevier
2015-01-01
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| Серія: | Neurobiology of Disease |
| Предмети: | |
| Онлайн доступ: | http://www.sciencedirect.com/science/article/pii/S0969996114003337 |