A Comparative Study to Evaluate the Effect of Different Carbohydrates on the Stability of Immunoglobulin G during Lyophilization and Following Storage

A Comparative Study to Evaluate the Effect of Different Carbohydrates on the Stability of Immunoglobulin G during Lyophilization and Following Storage

Background: Although the stabilizing effects of cyclodextrins (CDs) on the liquid protein formulations have been proven, there is no comprehensive data on evaluation of their effects on the lyophilized antibody powders. In this study, the influence of two CD derivatives namely beta-cyclodextrin (βCD...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριος συγγραφέας:	Homa Faghihi 1, Sara Merrikhihaghi 1, Abdolhosein Ruholamini Najafabadi 1, Vahid Ramezani 2, Soroush Sardari 3, Alireza Vatanara 1 *
Μορφή:	Άρθρο
Γλώσσα:	English
Έκδοση:	Tabriz University of Medical Sciences 2016-12-01
Σειρά:	Pharmaceutical Sciences
Θέματα:	Antibody Lyophilization Mannitol Trehalose Cyclodextrins Stability
Διαθέσιμο Online:	http://journals.tbzmed.ac.ir/PHARM/Abstract/PHARM_4075_20160317105357

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