Comparative immune phenotypic analysis of cutaneous Squamous Cell Carcinoma and Intraepidermal Carcinoma in immune-competent individuals: proportional representation of CD8+ T-cells but not FoxP3+ Regulatory T-cells is associated with disease stage.
Squamous Cell Carcinoma (SCC) is a type of non-melanoma skin cancer prevalent in immune-suppressed transplant recipients and older individuals with a history of chronic sun-exposure. SCC itself is believed to be a late-stage manifestation that can develop from premalignant lesions including Intraepi...
Main Authors: | Andrew Freeman, Jennifer A Bridge, Pirashanthini Maruthayanar, Nana H Overgaard, Ji-Won Jung, Fiona Simpson, Tarl W Prow, H Peter Soyer, Ian H Frazer, Michael Freeman, James W Wells |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4207854?pdf=render |
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