The NMR2 Method to Determine Rapidly the Structure of the Binding Pocket of a Protein–Ligand Complex with High Accuracy

Structural characterization of complexes is crucial for a better understanding of biological processes and structure-based drug design. However, many protein–ligand structures are not solvable by X-ray crystallography, for example those with low affinity binders or dynamic binding sites. Such comple...

Full description

Bibliographic Details
Main Authors: Marielle Aulikki Wälti, Julien Orts
Format: Article
Language:English
Published: MDPI AG 2018-01-01
Series:Magnetochemistry
Subjects:
Online Access:http://www.mdpi.com/2312-7481/4/1/12