Expanded disability status scale in Multiple Sclerosis: Relationship to visual evoked potential

Background: Multiple sclerosis (MS) prevalence in Iraq is 11.73/100,000 it causes disability in younger adults. Expanded Disability Status Scale (EDSS) can monitor MS disability while Visually Evoked Potentials (VEP) serves as a marker of myelination. Objectives: To explore the relationship betwe...

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Main Authors: rand salih, Hanan L. Al-Omary
Format: Article
Language:English
Published: College of Medicine University of Baghdad 2022-07-01
Series:مجلة كلية الطب
Online Access:https://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/1925
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author rand salih
Hanan L. Al-Omary
author_facet rand salih
Hanan L. Al-Omary
author_sort rand salih
collection DOAJ
description Background: Multiple sclerosis (MS) prevalence in Iraq is 11.73/100,000 it causes disability in younger adults. Expanded Disability Status Scale (EDSS) can monitor MS disability while Visually Evoked Potentials (VEP) serves as a marker of myelination. Objectives: To explore the relationship between EDSS and VEPs in multiple sclerosis patients. Patients and Methods: A cross-sectional study was conducted in Ghazi Al- Hariri Hospital from first of Nov 2021 till the end of Jan 2022. Fifty patients with multiple sclerosis were compared to 50 healthy individuals. EDSS Data were collected using a structured questionnaire, P100 latency were measured using VEP. The Correlation was used to investigate the relationship between P100- latencies and EDSS. P value ≤0.05 was considered significant. Results: The average age of MS cases was 33.5±8.01 years, and the mean EDSS was 2.8±2.86. A significant difference in the latency period was reported. The study showed a significant positive correlation between EDSS and P100 latency period. Conclusions: Using non-invasive procedures like VEPs can help to monitor and detect deterioration and improvement in MS patients.
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spelling doaj.art-cdcf6b698fc84805bb5e4ebdd23ee8d52024-01-02T06:37:03ZengCollege of Medicine University of Baghdadمجلة كلية الطب0041-94192410-80572022-07-0164210.32007/jfacmedbagdad.6421925Expanded disability status scale in Multiple Sclerosis: Relationship to visual evoked potentialrand salih0Hanan L. Al-Omary1department of physiology/college of medicineDepartment of physiology, College of Medicine – University of Baghdad Background: Multiple sclerosis (MS) prevalence in Iraq is 11.73/100,000 it causes disability in younger adults. Expanded Disability Status Scale (EDSS) can monitor MS disability while Visually Evoked Potentials (VEP) serves as a marker of myelination. Objectives: To explore the relationship between EDSS and VEPs in multiple sclerosis patients. Patients and Methods: A cross-sectional study was conducted in Ghazi Al- Hariri Hospital from first of Nov 2021 till the end of Jan 2022. Fifty patients with multiple sclerosis were compared to 50 healthy individuals. EDSS Data were collected using a structured questionnaire, P100 latency were measured using VEP. The Correlation was used to investigate the relationship between P100- latencies and EDSS. P value ≤0.05 was considered significant. Results: The average age of MS cases was 33.5±8.01 years, and the mean EDSS was 2.8±2.86. A significant difference in the latency period was reported. The study showed a significant positive correlation between EDSS and P100 latency period. Conclusions: Using non-invasive procedures like VEPs can help to monitor and detect deterioration and improvement in MS patients. https://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/1925
spellingShingle rand salih
Hanan L. Al-Omary
Expanded disability status scale in Multiple Sclerosis: Relationship to visual evoked potential
مجلة كلية الطب
title Expanded disability status scale in Multiple Sclerosis: Relationship to visual evoked potential
title_full Expanded disability status scale in Multiple Sclerosis: Relationship to visual evoked potential
title_fullStr Expanded disability status scale in Multiple Sclerosis: Relationship to visual evoked potential
title_full_unstemmed Expanded disability status scale in Multiple Sclerosis: Relationship to visual evoked potential
title_short Expanded disability status scale in Multiple Sclerosis: Relationship to visual evoked potential
title_sort expanded disability status scale in multiple sclerosis relationship to visual evoked potential
url https://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/1925
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