EFFECT OF ALENDRONATE COMBINED WITH ALFACALCIDOL ON THE BIOLOGICAL STABILITY OF HIP JOINT ENDOPROSTHESIS IN PATIENTS WITH SYSTEMIC OSTEOPOROSIS

In a comparative study we investigated the influence of a combination of alendronate and alfacalcidol on the dynamics of bone mass density (BMD) at the site attached to the femoral component of endoprosthesis in total hip replacement in patients with systemic osteoporosis. Evaluation of performance...

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Main Authors: S S Rodionova, T N Turgumbayev
Format: Article
Language:English
Published: Endocrinology Research Centre 2013-12-01
Series:Остеопороз и остеопатии
Subjects:
Online Access:https://endojournals.ru/index.php/osteo/article/view/8845
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author S S Rodionova
T N Turgumbayev
author_facet S S Rodionova
T N Turgumbayev
author_sort S S Rodionova
collection DOAJ
description In a comparative study we investigated the influence of a combination of alendronate and alfacalcidol on the dynamics of bone mass density (BMD) at the site attached to the femoral component of endoprosthesis in total hip replacement in patients with systemic osteoporosis. Evaluation of performance of pharmacotherapy in the postoperative period on osteoporosis, systemic osteoporosis, sustained BMD deficit at Gruen regions confirmed that the essential component of osteointegration at the «implant-bone» site during the period of physiological adaptive remodeling after arthroplasty in women suffering from systemic osteoporosis is the pharmacological correction of the intensity of bone resorption in post-operative period.
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spelling doaj.art-cdd0123d6aa24e82b5171410fcb979e82022-12-21T18:23:45ZengEndocrinology Research CentreОстеопороз и остеопатии2072-26802311-07162013-12-01161242810.14341/osteo2013124-287890EFFECT OF ALENDRONATE COMBINED WITH ALFACALCIDOL ON THE BIOLOGICAL STABILITY OF HIP JOINT ENDOPROSTHESIS IN PATIENTS WITH SYSTEMIC OSTEOPOROSISS S Rodionova0T N Turgumbayev1ФГБУ «Центральный научно-исследовательский институт травматологии и ортопедии имени Н.Н. Приорова» МЗ РФФГБУ «Центральный научно-исследовательский институт травматологии и ортопедии имени Н.Н. Приорова» МЗ РФIn a comparative study we investigated the influence of a combination of alendronate and alfacalcidol on the dynamics of bone mass density (BMD) at the site attached to the femoral component of endoprosthesis in total hip replacement in patients with systemic osteoporosis. Evaluation of performance of pharmacotherapy in the postoperative period on osteoporosis, systemic osteoporosis, sustained BMD deficit at Gruen regions confirmed that the essential component of osteointegration at the «implant-bone» site during the period of physiological adaptive remodeling after arthroplasty in women suffering from systemic osteoporosis is the pharmacological correction of the intensity of bone resorption in post-operative period.https://endojournals.ru/index.php/osteo/article/view/8845остеопорозэндопротезирование тазобедренного суставаалендронатальфакальцидолкоррекция интенсивности резорбции и костеобразования
spellingShingle S S Rodionova
T N Turgumbayev
EFFECT OF ALENDRONATE COMBINED WITH ALFACALCIDOL ON THE BIOLOGICAL STABILITY OF HIP JOINT ENDOPROSTHESIS IN PATIENTS WITH SYSTEMIC OSTEOPOROSIS
Остеопороз и остеопатии
остеопороз
эндопротезирование тазобедренного сустава
алендронат
альфакальцидол
коррекция интенсивности резорбции и костеобразования
title EFFECT OF ALENDRONATE COMBINED WITH ALFACALCIDOL ON THE BIOLOGICAL STABILITY OF HIP JOINT ENDOPROSTHESIS IN PATIENTS WITH SYSTEMIC OSTEOPOROSIS
title_full EFFECT OF ALENDRONATE COMBINED WITH ALFACALCIDOL ON THE BIOLOGICAL STABILITY OF HIP JOINT ENDOPROSTHESIS IN PATIENTS WITH SYSTEMIC OSTEOPOROSIS
title_fullStr EFFECT OF ALENDRONATE COMBINED WITH ALFACALCIDOL ON THE BIOLOGICAL STABILITY OF HIP JOINT ENDOPROSTHESIS IN PATIENTS WITH SYSTEMIC OSTEOPOROSIS
title_full_unstemmed EFFECT OF ALENDRONATE COMBINED WITH ALFACALCIDOL ON THE BIOLOGICAL STABILITY OF HIP JOINT ENDOPROSTHESIS IN PATIENTS WITH SYSTEMIC OSTEOPOROSIS
title_short EFFECT OF ALENDRONATE COMBINED WITH ALFACALCIDOL ON THE BIOLOGICAL STABILITY OF HIP JOINT ENDOPROSTHESIS IN PATIENTS WITH SYSTEMIC OSTEOPOROSIS
title_sort effect of alendronate combined with alfacalcidol on the biological stability of hip joint endoprosthesis in patients with systemic osteoporosis
topic остеопороз
эндопротезирование тазобедренного сустава
алендронат
альфакальцидол
коррекция интенсивности резорбции и костеобразования
url https://endojournals.ru/index.php/osteo/article/view/8845
work_keys_str_mv AT ssrodionova effectofalendronatecombinedwithalfacalcidolonthebiologicalstabilityofhipjointendoprosthesisinpatientswithsystemicosteoporosis
AT tnturgumbayev effectofalendronatecombinedwithalfacalcidolonthebiologicalstabilityofhipjointendoprosthesisinpatientswithsystemicosteoporosis