Detecting radio- and chemoresistant cells in 3D cancer co-cultures using chromatin biomarkers

Detecting radio- and chemoresistant cells in 3D cancer co-cultures using chromatin biomarkers

Abstract The heterogenous treatment response of tumor cells limits the effectiveness of cancer therapy. While this heterogeneity has been linked to cell-to-cell variability within the complex tumor microenvironment, a quantitative biomarker that identifies and characterizes treatment-resistant cell...

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Bibliographic Details
Main Authors:	Tina Pekeč, Saradha Venkatachalapathy, Anne R. Shim, Daniel Paysan, Michal Grzmil, Roger Schibli, Martin Béhé, G. V. Shivashankar
Format:	Article
Language:	English
Published:	Nature Portfolio 2023-11-01
Series:	Scientific Reports
Online Access:	https://doi.org/10.1038/s41598-023-47287-2

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