Cholesteryl oleyl and linoleyl ethers do not trace their ester counterparts in animals with plasma cholesteryl ester transfer activity.
Cholesteryl ethers are nonhydrolyzable tracers of cholesteryl esters. We report here that the ethers are not legitimate tracers of esters in systems involving plasma cholesteryl ester transfer activity. On intravenous injection of doubly labeled high density lipoproteins into rabbits, cholesteryl es...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
1989-09-01
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| Series: | Journal of Lipid Research |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520382638 |
| _version_ | 1818941917994418176 |
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| author | S R Green W F Beltz D I Goldberg R C Pittman |
| author_facet | S R Green W F Beltz D I Goldberg R C Pittman |
| author_sort | S R Green |
| collection | DOAJ |
| description | Cholesteryl ethers are nonhydrolyzable tracers of cholesteryl esters. We report here that the ethers are not legitimate tracers of esters in systems involving plasma cholesteryl ester transfer activity. On intravenous injection of doubly labeled high density lipoproteins into rabbits, cholesteryl ester tracer was more rapidly transferred to other lipoprotein fractions than was cholesteryl ether tracer. In direct assays in vitro, the rate of transfer of esters was about two times that of the ether. This difference was not due to tracer impurity or lability of 3H, did not depend on the nature of the donor or acceptor lipoprotein, and was similar for cholesteryl ester transfer activities of both human and rabbit origin. |
| first_indexed | 2024-12-20T07:03:10Z |
| format | Article |
| id | doaj.art-cdd3c88c810140eb92c6e53ecf6b2ded |
| institution | Directory Open Access Journal |
| issn | 0022-2275 |
| language | English |
| last_indexed | 2024-12-20T07:03:10Z |
| publishDate | 1989-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Lipid Research |
| spelling | doaj.art-cdd3c88c810140eb92c6e53ecf6b2ded2022-12-21T19:49:09ZengElsevierJournal of Lipid Research0022-22751989-09-0130914051410Cholesteryl oleyl and linoleyl ethers do not trace their ester counterparts in animals with plasma cholesteryl ester transfer activity.S R Green0W F Beltz1D I Goldberg2R C Pittman3Department of Medicine, University of California, San Diego, La Jolla 92093.Department of Medicine, University of California, San Diego, La Jolla 92093.Department of Medicine, University of California, San Diego, La Jolla 92093.Department of Medicine, University of California, San Diego, La Jolla 92093.Cholesteryl ethers are nonhydrolyzable tracers of cholesteryl esters. We report here that the ethers are not legitimate tracers of esters in systems involving plasma cholesteryl ester transfer activity. On intravenous injection of doubly labeled high density lipoproteins into rabbits, cholesteryl ester tracer was more rapidly transferred to other lipoprotein fractions than was cholesteryl ether tracer. In direct assays in vitro, the rate of transfer of esters was about two times that of the ether. This difference was not due to tracer impurity or lability of 3H, did not depend on the nature of the donor or acceptor lipoprotein, and was similar for cholesteryl ester transfer activities of both human and rabbit origin.http://www.sciencedirect.com/science/article/pii/S0022227520382638 |
| spellingShingle | S R Green W F Beltz D I Goldberg R C Pittman Cholesteryl oleyl and linoleyl ethers do not trace their ester counterparts in animals with plasma cholesteryl ester transfer activity. Journal of Lipid Research |
| title | Cholesteryl oleyl and linoleyl ethers do not trace their ester counterparts in animals with plasma cholesteryl ester transfer activity. |
| title_full | Cholesteryl oleyl and linoleyl ethers do not trace their ester counterparts in animals with plasma cholesteryl ester transfer activity. |
| title_fullStr | Cholesteryl oleyl and linoleyl ethers do not trace their ester counterparts in animals with plasma cholesteryl ester transfer activity. |
| title_full_unstemmed | Cholesteryl oleyl and linoleyl ethers do not trace their ester counterparts in animals with plasma cholesteryl ester transfer activity. |
| title_short | Cholesteryl oleyl and linoleyl ethers do not trace their ester counterparts in animals with plasma cholesteryl ester transfer activity. |
| title_sort | cholesteryl oleyl and linoleyl ethers do not trace their ester counterparts in animals with plasma cholesteryl ester transfer activity |
| url | http://www.sciencedirect.com/science/article/pii/S0022227520382638 |
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