New protocol for kinetic assay seeding ability recovery “KASAR” from formalin-fixed paraffin-embedded tissues

The real-time quaking-induced conversion (RT-QuIC) alpha-synuclein (aSyn) protein kinetic seeding assay has been very useful for detecting pathological aggregates in various synucleinopathies including Parkinson’s disease (PD). This biomarker assay relies on fresh frozen tissue to effectively seed a...

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Bibliografische gegevens
Hoofdauteurs: Monica Hepker, Griffin Clabaugh, Huajun Jin, Anumantha G. Kanthasamy
Formaat: Artikel
Taal:English
Gepubliceerd in: Frontiers Media S.A. 2023-01-01
Reeks:Frontiers in Molecular Biosciences
Onderwerpen:
Online toegang:https://www.frontiersin.org/articles/10.3389/fmolb.2023.1087982/full