New protocol for kinetic assay seeding ability recovery “KASAR” from formalin-fixed paraffin-embedded tissues

The real-time quaking-induced conversion (RT-QuIC) alpha-synuclein (aSyn) protein kinetic seeding assay has been very useful for detecting pathological aggregates in various synucleinopathies including Parkinson’s disease (PD). This biomarker assay relies on fresh frozen tissue to effectively seed a...

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Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Monica Hepker, Griffin Clabaugh, Huajun Jin, Anumantha G. Kanthasamy
Formáid: Alt
Teanga:English
Foilsithe / Cruthaithe: Frontiers Media S.A. 2023-01-01
Sraith:Frontiers in Molecular Biosciences
Ábhair:
Rochtain ar líne:https://www.frontiersin.org/articles/10.3389/fmolb.2023.1087982/full