ATR protects ongoing and newly assembled DNA replication forks through distinct mechanisms

ATR protects ongoing and newly assembled DNA replication forks through distinct mechanisms

Summary: The ATR kinase safeguards genomic integrity during S phase, but how ATR protects DNA replication forks remains incompletely understood. Here, we combine four distinct assays to analyze ATR functions at ongoing and newly assembled replication forks upon replication inhibition by hydroxyurea....

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Wendy Leung, Antoine Simoneau, Sneha Saxena, Jessica Jackson, Parasvi S. Patel, Mangsi Limbu, Alessandro Vindigni, Lee Zou
Format: Artykuł
Język:English
Wydane: Elsevier 2023-07-01
Seria:Cell Reports
Hasła przedmiotowe:
CP: Molecular biology
Dostęp online:http://www.sciencedirect.com/science/article/pii/S2211124723008033

Internet

http://www.sciencedirect.com/science/article/pii/S2211124723008033

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