End-condition for solution small angle X-ray scattering measurements by kernel density estimation
We develop a method for calculating the minimum X-ray exposure time for X-ray solution scattering experiments using statistical and mathematical approaches to enhance the measurement efficiency while maintaining data quality. Experts can determine the X-ray exposure time for samples by investigating...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2022-12-01
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Series: | Science and Technology of Advanced Materials: Methods |
Subjects: | |
Online Access: | http://dx.doi.org/10.1080/27660400.2022.2140021 |
Summary: | We develop a method for calculating the minimum X-ray exposure time for X-ray solution scattering experiments using statistical and mathematical approaches to enhance the measurement efficiency while maintaining data quality. Experts can determine the X-ray exposure time for samples by investigating time-series data of scattering profiles and considering the quality of scattering profiles and the samples’ X-ray damage. In this study, we apply a statistical inequality to estimate the kernel density estimation method’s error to determine the minimum X-ray exposure time for protein solution scattering experiments and evaluate the method’s validity using the results of Guinier analysis as an indicator. |
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ISSN: | 2766-0400 |